[HTML][HTML] Recent Developments Towards the Synthesis of Triazole Derivatives: A Review
I Ameziane El Hassani, K Rouzi… - Organics, 2024 - mdpi.com
The triazole scaffold is a crucial component of heterocyclic chemistry, serving as a basic
building block in organic synthesis, materials science, and medicinal chemistry. Triazole is a …
building block in organic synthesis, materials science, and medicinal chemistry. Triazole is a …
Spiro-fused indoline-quinazoline hybrids as smart bombs against TNF-α-mediated inflammation
Inflammation is central to numerous diseases, highlighting the need for new anti-
inflammatory agents. This study explores the potential of novel spirofused indoline …
inflammatory agents. This study explores the potential of novel spirofused indoline …
Discovery of new quinoline derivatives bearing 1-aryl-1, 2, 3-triazole motif as influenza H1N1 virus neuraminidase inhibitors
Sporadically and periodically, influenza outbreaks threaten global health and the economy.
Antigen drift-induced influenza virus mutations hamper antiviral drug development. Thus, a …
Antigen drift-induced influenza virus mutations hamper antiviral drug development. Thus, a …
Fragment-based design and synthesis of coumarin-based thiazoles as dual c-MET/STAT-3 inhibitors for potential antitumor agents
Abstract c-MET and STAT-3 are significant targets for cancer treatments. Here, we describe
a class of very effective dual STAT-3 and c-MET inhibitors with coumarin-based thiazoles …
a class of very effective dual STAT-3 and c-MET inhibitors with coumarin-based thiazoles …
Exploring antitumor activity of novel imidazo [2, 1-b] thiazole and imidazo [1, 2-a] pyridine derivatives on MDA-MB-231 cell line: Targeting VEGFR-2 enzyme with …
Our study explored the anticancer potential of novel heterocyclic compounds, specifically 6a-
d, 8a-d, 12a-d, and 13a-d, which are derived from imidazo [2, 1-b] thiazole and imidazo [1, 2 …
d, 8a-d, 12a-d, and 13a-d, which are derived from imidazo [2, 1-b] thiazole and imidazo [1, 2 …