Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects

EB Hunziker - Osteoarthritis and cartilage, 2002 - Elsevier
Objective To review the basic scientific status of repair in articular cartilage tissue and to
assess the efficiency of current clinical therapies instigated for the treatment of structural …

Tissue engineered bone grafts: biological requirements, tissue culture and clinical relevance

M Frohlich, WL Grayson, LQ Wan… - Current stem cell …, 2008 - benthamdirect.com
The tremendous need for bone tissue in numerous clinical situations and the limited
availability of suitable bone grafts are driving the development of tissue engineering …

Responsive hydrogels from the intramolecular folding and self-assembly of a designed peptide

JP Schneider, DJ Pochan, B Ozbas… - Journal of the …, 2002 - ACS Publications
A general peptide design is presented that links the pH-dependent intramolecular folding of
β-hairpin peptides to their propensity to self-assemble, affording hydrogels rich in β-sheet …

A three-dimensional nanofibrous scaffold for cartilage tissue engineering using human mesenchymal stem cells

WJ Li, R Tuli, C Okafor, A Derfoul, KG Danielson… - Biomaterials, 2005 - Elsevier
The utilization of adult stem cells in tissue engineering is a promising solution to the problem
of tissue or organ shortage. Adult bone marrow derived mesenchymal stem cells (MSCs) are …

Control of degradation rate and hydrophilicity in electrospun non-woven poly (D, L-lactide) nanofiber scaffolds for biomedical applications

K Kim, M Yu, X Zong, J Chiu, D Fang, YS Seo… - Biomaterials, 2003 - Elsevier
Typical properties of poly (d, l-lactide)(PLA)-based scaffolds (films and foams), such as long
degradation time, mechanical stiffness and hydrophobicity, are sometimes not suitable for …

[HTML][HTML] Chondrogenic differentiation and functional maturation of bovine mesenchymal stem cells in long-term agarose culture

RL Mauck, X Yuan, RS Tuan - Osteoarthritis and cartilage, 2006 - Elsevier
BACKGROUND: The developmental history of the chondrocyte results in a cell whose
biosynthetic activities are optimized to maintain the concentration and organization of a …

Bone tissue engineering using human mesenchymal stem cells: effects of scaffold material and medium flow

L Meinel, V Karageorgiou, R Fajardo, B Snyder… - Annals of biomedical …, 2004 - Springer
We report studies of bone tissue engineering using human mesenchymal stem cells (MSCs),
a protein substrate (film or scaffold; fast degrading unmodified collagen, or slowly degrading …

Silk implants for the healing of critical size bone defects

L Meinel, R Fajardo, S Hofmann, R Langer, J Chen… - Bone, 2005 - Elsevier
Bone (re)-generation and bone fixation strategies utilize biomaterial implants, which are
gradually replaced by autologous tissues. Ideally, these biomaterials should be …

Effect of ascorbic acid on bone marrow-derived mesenchymal stem cell proliferation and differentiation

KM Choi, YK Seo, HH Yoon, KY Song, SY Kwon… - Journal of bioscience …, 2008 - Elsevier
Mesenchymal stem cells (MSCs) derived from bone marrow are an important tool in tissue
engineering and cell-based therapies because of their multipotent capacity. Majority of …

Formation of three‐dimensional cell/polymer constructs for bone tissue engineering in a spinner flask and a rotating wall vessel bioreactor

VI Sikavitsas, GN Bancroft… - Journal of Biomedical …, 2002 - Wiley Online Library
The aim of this study is to investigate the effect of the cell culture conditions of three‐
dimensional polymer scaffolds seeded with rat marrow stromal cells (MSCs) cultured in …