Sarcopenia is a loss of muscle mass and function in the elderly that reduces mobility,
diminishes quality of life, and can lead to fall-related injuries, which require costly …

Adult skeletal muscle in mammals is a stable tissue under normal circumstances but has
remarkable ability to repair after injury. Skeletal muscle regeneration is a highly orchestrated …

The growth of blood vessels (a process known as angiogenesis) is essential for organ
growth and repair. An imbalance in this process contributes to numerous malignant …

Skeletal muscles are essential for vital functions such as movement, postural support,
breathing, and thermogenesis. Muscle tissue is largely composed of long, postmitotic …

MicroRNAs (miRNAs) are small non-protein-coding RNAs that function as negative gene
expression regulators. In the present study, we investigated miRNAs role in endothelial cell …

Enabling angiogenesis is critical for the success of tissue repair therapies and the fate of
tissue-engineered constructs. Although many biochemical signaling molecules have been …

Genetically engineered mice (Myf5 nLacZ/+, Myf5 GFP-P/+) allowing direct muscle satellite
cell (SC) visualization indicate that, in addition to being located beneath myofiber basal …

The use of fetal bovine serum (FBS) in animal cell culture media is widely spread since it
provides a broad spectrum of molecules that are known to support cell attachment and …

In skeletal muscle, new functions for vessels have recently emerged beyond oxygen and
nutrient supply, through the interactions that vascular cells establish with muscle stem cells …

Skeletal muscle tissue engineering (SMTE) aims to repair or regenerate defective skeletal
muscle tissue lost by traumatic injury, tumor ablation, or muscular disease. However, two …