Metabolic syndrome (MetS) is a cluster of cardiometabolic risk factors with high prevalence
among adult populations and elevated costs for public health systems worldwide. Despite …

Obesity leads to an inflammatory condition that is directly involved in the etiology of
cardiovascular diseases, type 2 diabetes mellitus, and certain types of cancer. The classic …

Obesity increases the risk of cardiovascular disease and premature death. Adipose tissue
releases a large number of bioactive mediators that influence not only body weight …

OBJECTIVE—We sought to determine the role of adipocyte death in obesity-induced
adipose tissue (AT) inflammation and obesity complications. RESEARCH DESIGN AND …

Sarcopenia is the loss of skeletal muscle mass and function with advancing age. It involves
both complex genetic and modifiable risk factors, such as lack of exercise, malnutrition and …

As humans evolved, perhaps the two strongest selection determinants of survival were a
robust immune response able to clear bacterial, viral, and parasitic infection and an ability to …

The incidence of obesity has increased dramatically during recent decades. Obesity will
cause a decline in life expectancy for the first time in recent history due to numerous co …

Obesity is an energy‐rich condition associated with overnutrition, which impairs systemic
metabolic homeostasis and elicits stress. It also activates an inflammatory process in …

Type 2 diabetes mellitus (T2DM) is a worldwide epidemic, which by all predictions will only
increase. To help in combating the devastating array of phenotypes associated with T2DM a …

Inflammation is a stereotypical physiological response to infections and tissue injury; it
initiates pathogen killing as well as tissue repair processes and helps to restore …