Astrocyte‐mediated mechanisms contribute to traumatic brain injury pathology

C Muñoz‐Ballester, S Robel - WIREs mechanisms of disease, 2023 - Wiley Online Library
Astrocytes respond to traumatic brain injury (TBI) with changes to their molecular make‐up
and cell biology, which results in changes in astrocyte function. These changes can be …

The role of microRNA in traumatic brain injury

YB Pan, ZL Sun, DF Feng - Neuroscience, 2017 - Elsevier
Traumatic brain injury (TBI) is a public health problem that causes high mortality and
disability worldwide. Secondary brain damage from this type of injury may cause brain …

Inhibition of ferroptosis attenuates tissue damage and improves long‐term outcomes after traumatic brain injury in mice

BS **e, YQ Wang, Y Lin, Q Mao, JF Feng… - CNS neuroscience & …, 2019 - Wiley Online Library
Aims Ferroptosis, a new form of iron‐dependent programmed cell death, has been shown to
be involved in a range of diseases. However, the role of ferroptosis in traumatic brain injury …

Repetitive diffuse mild traumatic brain injury causes an atypical astrocyte response and spontaneous recurrent seizures

O Shandra, AR Winemiller, BP Heithoff… - Journal of …, 2019 - jneurosci.org
Focal traumatic brain injury (TBI) induces astrogliosis, a process essential to protecting
uninjured brain areas from secondary damage. However, astrogliosis can cause loss of …

From physiology to pathology of astrocytes: highlighting their potential as therapeutic targets for CNS injury

Y Yuan, H Liu, Z Dai, C He, S Qin, Z Su - Neuroscience Bulletin, 2024 - Springer
In the mammalian central nervous system (CNS), astrocytes are the ubiquitous glial cells
that have complex morphological and molecular characteristics. These fascinating cells play …

MicroRNAs: the new challenge for traumatic brain injury diagnosis

E Pinchi, C Luigi, S Paola, V Gianpietro… - Current …, 2020 - benthamdirect.com
The acronym TBI refers to traumatic brain injury, an alteration of brain function, or an
evidence of brain pathology, that is caused by an external force. TBI is estimated to become …

Estrogen formation and inactivation following TBI: what we know and where we could go

KA Duncan - Frontiers in endocrinology, 2020 - frontiersin.org
Traumatic brain injury (TBI) is responsible for various neuronal and cognitive deficits as well
as psychosocial dysfunction. Characterized by damage inducing neuroinflammation, this …

Post-traumatic stress disorder in adult victims of cluster munitions in Lebanon: a 10-year longitudinal study

J Fares, S Gebeily, M Saad, H Harati, S Nabha… - BMJ open, 2017 - bmjopen.bmj.com
Objective This study aims to explore the short-term and long-term prevalence and effects of
post-traumatic stress disorder (PTSD) among victims of cluster munitions. Design and setting …

Minocycline attenuates neuronal apoptosis and improves motor function after traumatic brain injury in rats

J He, J Mao, L Hou, S **, X Wang, Z Ding, Z **… - Experimental …, 2021 - jstage.jst.go.jp
Minocycline is a type of tetracycline antibiotic with broad-spectrum antibacterial activity that
has been demonstrated to protect the brain against a series of central nervous system …

Targeting NRF2 to suppress ferroptosis in brain injury

S Song, Y Gao, Y Sheng, T Rui, C Luo - 2021 - digitum.um.es
y. Brain injury is accompanied by serious iron metabolism disorder and oxidative stress. As
a novel form of regulated cell death (RCD) depending on lipid peroxidation caused by iron …