Experimental models of epilepsy are useful to identify potential mechanisms of
epileptogenesis, seizure genesis, comorbidities, and treatment efficacy. The kainic acid (KA) …

Mesial temporal lobe epilepsy is the most common form of human epilepsy, and its
pathophysiological substrate is usually hippocampal sclerosis, the most common …

Hippocampal sclerosis (HS) is the most frequent histopathology encountered in patients with
drug‐resistant temporal lobe epilepsy (TLE). Over the past decades, various attempts have …

In order to understand the pathophysiology of temporal lobe epilepsy (TLE), and thus to
develop new pharmacological treatments, in vivo animal models that present features …

During the past decade, it has become apparent that neural circuits undergo activity-
dependent reorganisation. In pathological disorders with recurring episodes of excessive …

This new book, The Epilepsies, details the most recent advances in epileptic seizures,
epileptic syndromes and their management. It is based on the International League Against …

I would also like to thank Ian Stoneham, Publisher, and his team, particularly Hannah Cole
and Nadine Lemmens, Editors, and Keith Baker, Designer; their professionalism, dedication …

There is little information available relevant to long-term seizure outcome after anterior
temporal lobectomy, particularly at extended postoperative periods. The aim of this study …

Febrile seizures are the most common form of childhood seizures, occurring in 2 to 5% of
children in the United States. Most febrile seizures are considered simple, although those …

Temporal lobe epilepsy (TLE) is frequently associated with hippocampal sclerosis, possibly
caused by a primary brain injury that occurred a long time before the appearance of …