Ice inhibition for cryopreservation: materials, strategies, and challenges

T Chang, G Zhao - Advanced Science, 2021 - Wiley Online Library
Cryopreservation technology has developed into a fundamental and important supporting
method for biomedical applications such as cell‐based therapeutics, tissue engineering …

The promise of organ and tissue preservation to transform medicine

S Giwa, JK Lewis, L Alvarez, R Langer, AE Roth… - Nature …, 2017 - nature.com
The ability to replace organs and tissues on demand could save or improve millions of lives
each year globally and create public health benefits on par with curing cancer. Unmet needs …

Vitrification and nanowarming enable long-term organ cryopreservation and life-sustaining kidney transplantation in a rat model

Z Han, JS Rao, L Gangwar, BE Namsrai… - Nature …, 2023 - nature.com
Banking cryopreserved organs could transform transplantation into a planned procedure
that more equitably reaches patients regardless of geographical and time constraints …

Cryoprotectants: A review of the actions and applications of cryoprotective solutes that modulate cell recovery from ultra-low temperatures

GD Elliott, S Wang, BJ Fuller - Cryobiology, 2017 - Elsevier
Cryopreservation has become a central technology in many areas of clinical medicine,
biotechnology, and species conservation within both plant and animal biology …

Cryoprotectant toxicity: facts, issues, and questions

BP Best - Rejuvenation research, 2015 - liebertpub.com
High levels of penetrating cryoprotectants (CPAs) can eliminate ice formation during
cryopreservation of cells, tissues, and organs to cryogenic temperatures. But CPAs become …

[HTML][HTML] Restoration of ovarian activity and pregnancy after transplantation of cryopreserved ovarian tissue: a review of 60 cases of reimplantation

J Donnez, MM Dolmans, A Pellicer, C Diaz-Garcia… - Fertility and sterility, 2013 - Elsevier
Aggressive chemotherapy/radiotherapy and bone marrow transplantation can cure> 90% of
girls and young women affected by disorders requiring such treatment. However, the ovaries …

Synthetic polymers enable non-vitreous cellular cryopreservation by reducing ice crystal growth during thawing

RC Deller, M Vatish, DA Mitchell, MI Gibson - Nature communications, 2014 - nature.com
The cryopreservation of cells, tissue and organs is fundamental to modern biotechnology,
transplantation medicine and chemical biology. The current state-of-the-art method of …

New approaches to cryopreservation of cells, tissues, and organs

MJ Taylor, BP Weegman, SC Baicu… - Transfusion Medicine and …, 2019 - karger.com
In this concept article, we outline a variety of new approaches that have been conceived to
address some of the remaining challenges for develo** improved methods of …

-Principles of Cryopreservation

DE Pegg - PreservAtion of HumAn oocytes, 2009 - taylorfrancis.com
Several reviews of the biophysical principles of cryobiology have been published recently
and the interested reader is referred particularly to Mazur (1) for a detailed discussion or to …

Partial freezing of rat livers extends preservation time by 5-fold

SN Tessier, RJ de Vries, CA Pendexter… - Nature …, 2022 - nature.com
The limited preservation duration of organs has contributed to the shortage of organs for
transplantation. Recently, a tripling of the storage duration was achieved with supercooling …