[HTML][HTML] Flavonoids—Natural gifts to promote health and longevity

X Fan, Z Fan, Z Yang, T Huang, Y Tong… - International journal of …, 2022 - mdpi.com
The aging of mammals is accompanied by the progressive atrophy of tissues and organs
and the accumulation of random damage to macromolecular DNA, protein, and lipids …

Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applications

Y Taheri, HAR Suleria, N Martins, O Sytar… - … medicine and therapies, 2020 - Springer
Several flavonoids have been recognized as nutraceuticals, and myricetin is a good
example. Myricetin is commonly found in plants and their antimicrobial and antioxidant …

Myricetin: a multifunctional flavonol in biomedicine

G Agraharam, A Girigoswami… - Current pharmacology …, 2022 - Springer
Abstract Purpose of Reveiw The root cause of many diseases like CVD, cancer, and aging is
free radicals which exert their effect by interfering with different metabolic pathways. The …

Dietary polyphenols represent a phytotherapeutic alternative for gut dysbiosis associated neurodegeneration: A Systematic review

A Chatterjee, S Kumar, SR Sarkar, R Halder… - The Journal of …, 2024 - Elsevier
Globally, neurodegeneration and cerebrovascular disease are common and growing
causes of morbidity and mortality. Pathophysiology of this group of diseases encompasses …

Closest horizons of Hsp70 engagement to manage neurodegeneration

AA Venediktov, OY Bushueva… - Frontiers in molecular …, 2023 - frontiersin.org
Our review seeks to elucidate the current state-of-the-art in studies of 70-kilodalton-weighed
heat shock proteins (Hsp70) in neurodegenerative diseases (NDs). The family has already …

Anti-oxidative, anti-inflammatory and anti-apoptotic effects of flavonols: targeting Nrf2, NF-κB and p53 pathways in neurodegeneration

M Jazvinšćak Jembrek, N Oršolić, L Mandić, A Sadžak… - Antioxidants, 2021 - mdpi.com
Neurodegenerative diseases are one of the leading causes of disability and death
worldwide. Intracellular transduction pathways that end in the activation of specific …

Flavonoids: Potential candidates for the treatment of neurodegenerative disorders

S Devi, V Kumar, SK Singh, AK Dubey, JJ Kim - Biomedicines, 2021 - mdpi.com
Neurodegenerative disorders, such as Parkinson's disease (PD), Alzheimer's disease (AD),
Amyotrophic lateral sclerosis (ALS), and Huntington's disease (HD), are the most concerning …

Zebrafish: A model deciphering the impact of flavonoids on neurodegenerative disorders

K Mhalhel, M Sicari, L Pansera, J Chen, M Levanti… - Cells, 2023 - mdpi.com
Over the past century, advances in biotechnology, biochemistry, and pharmacognosy have
spotlighted flavonoids, polyphenolic secondary metabolites that have the ability to modulate …

[HTML][HTML] Heat shock protein 70 (HSP70) induction: chaperonotherapy for neuroprotection after brain injury

JY Kim, S Barua, MY Huang, J Park, MA Yenari, JE Lee - Cells, 2020 - mdpi.com
The 70 kDa heat shock protein (HSP70) is a stress-inducible protein that has been shown to
protect the brain from various nervous system injuries. It allows cells to withstand potentially …

Protein aggregation and therapeutic strategies in SOD1-and TDP-43-linked ALS

M Tsekrekou, M Giannakou… - Frontiers in Molecular …, 2024 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with severe socio-
economic impact. A hallmark of ALS pathology is the presence of aberrant cytoplasmic …