Pulmonary hypertension

A Mocumbi, M Humbert, A Saxena, ZC **g… - Nature reviews Disease …, 2024 - nature.com
Pulmonary hypertension encompasses a range of conditions directly or indirectly leading to
elevated pressures within the pulmonary arteries. Five main groups of pulmonary …

Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives

M Humbert, C Guignabert, S Bonnet… - European …, 2019 - publications.ersnet.org
Clinical and translational research has played a major role in advancing our understanding
of pulmonary hypertension (PH), including pulmonary arterial hypertension and other forms …

The latest in animal models of pulmonary hypertension and right ventricular failure

O Boucherat, V Agrawal, A Lawrie, S Bonnet - Circulation research, 2022 - ahajournals.org
Pulmonary hypertension (PH) describes heterogeneous population of patients with a mean
pulmonary arterial pressure> 20 mm Hg. Rarely, PH presents as a primary disorder but is …

Genetics and genomics of pulmonary arterial hypertension

NW Morrell, MA Aldred, WK Chung… - European …, 2019 - publications.ersnet.org
Since 2000 there have been major advances in our understanding of the genetic and
genomics of pulmonary arterial hypertension (PAH), although there remains much to …

Pulmonary arterial hypertension: pathogenesis and clinical management

T Thenappan, ML Ormiston, JJ Ryan, SL Archer - Bmj, 2018 - bmj.com
Pulmonary hypertension is defined as a resting mean pulmonary artery pressure of 25 mm
Hg or above. This review deals with pulmonary arterial hypertension (PAH), a type of …

2015 ESC/ERS guidelines for the diagnosis and treatment of pulmonary hypertension: the joint task force for the diagnosis and treatment of pulmonary hypertension of …

N Galiè, M Humbert, JL Vachiery, S Gibbs… - European heart …, 2016 - academic.oup.com
Pulmonary hypertension (PH) is a pathophysiological disorder that may involve multiple
clinical conditions and can complicate the majority of cardiovascular and respiratory …

2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: Developed by the task force for the diagnosis and treatment of pulmonary …

M Humbert, G Kovacs, MM Hoeper… - European heart …, 2022 - academic.oup.com
Pulmonary hypertension (PH) is a pathophysiological disorder that may involve multiple
clinical conditions and may be associated with a variety of cardiovascular and respiratory …

Epidemiology and treatment of pulmonary arterial hypertension

EMT Lau, E Giannoulatou, DS Celermajer… - Nature Reviews …, 2017 - nature.com
In the past 2 decades, major changes have occurred in the epidemiological and treatment
landscape of pulmonary arterial hypertension (PAH). Previously regarded as a disease of …

Molecular genetic framework underlying pulmonary arterial hypertension

L Southgate, RD Machado, S Gräf… - Nature Reviews …, 2020 - nature.com
Pulmonary arterial hypertension (PAH) is a rare, progressive disorder typified by occlusion
of the pulmonary arterioles owing to endothelial dysfunction and uncontrolled proliferation of …

Definitions and diagnosis of pulmonary hypertension

MM Hoeper, HJ Bogaard, R Condliffe, R Frantz… - Journal of the American …, 2013 - jacc.org
Pulmonary hypertension (PH) is defined by a mean pulmonary artery pressure≥ 25 mm Hg
at rest, measured during right heart catheterization. There is still insufficient evidence to add …