Abstract Objectives Long noncoding RNAs (lncRNA) are a type of noncoding RNA that
comprise of longer than 200 nucleotides sequences. They can regulate chromosome …

Small molecules that directly target MYC and are also well tolerated in vivo will provide
invaluable chemical probes and potential anti-cancer therapeutic agents. We developed a …

Long non-coding RNA (lncRNA) DANCR (also known as ANCR)—differentiation
antagonizing non-protein coding RNA, was first reported in 2012 to suppress differentiation …

The major function of Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is to
regulate cell metabolism. However, emerging evidence indicates that IGF2BP2 plays a role …

Abstract Background Long non-coding RNAs (lncRNAs) have been associated with non-
small cell lung cancer (NSCLC), but the underlying molecular mechanisms of their specific …

Background TAMs (tumor-associated macrophages) infiltration promotes the progression of
esophageal cancer (EC). However, the underlying mechanisms remain unclear. Methods …

Natural killer (NK) cells are critical mediators of host immunity to pathogens. Here, we
demonstrate that the endoplasmic reticulum stress sensor inositol-requiring enzyme 1 …

Long noncoding RNAs (lncRNAs), by virtue of their versatility and multilevel gene regulation,
have emerged as attractive pharmacological targets for treating heterogeneous and …

Background Accumulating evidences have indicated that long non-coding RNAs (lncRNAs)
are potential biomarkers that play key roles in tumor development and progression …

Although thousands of long noncoding RNAs (lncRNAs) have been annotated, only a
limited number of them have been functionally characterized. Here, we identified an …