Macrophage defense mechanisms against intracellular bacteria
Macrophages and neutrophils play a decisive role in host responses to intracellular bacteria
including the agent of tuberculosis (TB), M ycobacterium tuberculosis as they represent the …
including the agent of tuberculosis (TB), M ycobacterium tuberculosis as they represent the …
Leishmania and the macrophage: a multifaceted interaction
M Podinovskaia, A Descoteaux - Future microbiology, 2015 - Taylor & Francis
Leishmania, the causative agent of leishmaniases, is an intracellular parasite of
macrophages, transmitted to humans via the bite of its sand fly vector. This protozoan …
macrophages, transmitted to humans via the bite of its sand fly vector. This protozoan …
Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense
INTRODUCTION In all eukaryotic cells, lipid droplets (LDs) store and supply essential lipids
to produce signaling molecules, membrane building blocks, and metabolic energy. The LD …
to produce signaling molecules, membrane building blocks, and metabolic energy. The LD …
Subcellular antibiotic visualization reveals a dynamic drug reservoir in infected macrophages
Tuberculosis, caused by the intracellular pathogen Mycobacterium tuberculosis, remains the
world's deadliest infectious disease. Sterilizing chemotherapy requires at least 6 months of …
world's deadliest infectious disease. Sterilizing chemotherapy requires at least 6 months of …
Sphingolipid metabolism during Toll‐like receptor 4 (TLR4)‐mediated macrophage activation
A Olona, C Hateley, S Muralidharan… - British journal of …, 2021 - Wiley Online Library
Macrophage activation in response to stimulation of Toll‐like receptor 4 (TLR4) provides a
paradigm for investigating energy metabolism that regulates the inflammatory response …
paradigm for investigating energy metabolism that regulates the inflammatory response …
Phospholipase A2 regulation of lipid droplet formation
The classical regard of lipid droplets as mere static energy-storage organelles has evolved
dramatically. Nowadays these organelles are known to participate in key processes of cell …
dramatically. Nowadays these organelles are known to participate in key processes of cell …
Host lipid droplets: An important source of lipids salvaged by the intracellular parasite Toxoplasma gondii
SJ Nolan, JD Romano, I Coppens - PLoS pathogens, 2017 - journals.plos.org
Toxoplasma is an obligate intracellular parasite that replicates in mammalian cells within a
parasitophorous vacuole (PV) that does not fuse with any host organelles. One mechanism …
parasitophorous vacuole (PV) that does not fuse with any host organelles. One mechanism …
Immunometabolism of Phagocytes During Mycobacterium tuberculosis Infection
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) remains as a leading killer
among infectious diseases worldwide. The nature of the host immune response dictates …
among infectious diseases worldwide. The nature of the host immune response dictates …
Lipid droplet, a key player in host-parasite interactions
Lipid droplets (lipid bodies, LDs) are dynamic organelles that have important roles in
regulating lipid metabolism, energy homeostasis, cell signaling, membrane trafficking, and …
regulating lipid metabolism, energy homeostasis, cell signaling, membrane trafficking, and …
Revolutionizing control strategies against Mycobacterium tuberculosis infection through selected targeting of lipid metabolism
H Kim, SJ Shin - Cellular and Molecular Life Sciences, 2023 - Springer
Lipid species play a critical role in the growth and virulence expression of Mycobacterium
tuberculosis (Mtb), the causative agent of tuberculosis (TB). During Mtb infection, foamy …
tuberculosis (Mtb), the causative agent of tuberculosis (TB). During Mtb infection, foamy …