[HTML][HTML] Beneficial outcomes of omega-6 and omega-3 polyunsaturated fatty acids on human health: An update for 2021

I Djuricic, PC Calder - Nutrients, 2021‏ - mdpi.com
Oxidative stress and inflammation have been recognized as important contributors to the risk
of chronic non-communicable diseases. Polyunsaturated fatty acids (PUFAs) may regulate …

[HTML][HTML] Malnutrition in older adults—recent advances and remaining challenges

K Norman, U Haß, M Pirlich - Nutrients, 2021‏ - mdpi.com
Malnutrition in older adults has been recognised as a challenging health concern
associated with not only increased mortality and morbidity, but also with physical decline …

Immunology of aging: the birth of inflammaging

T Fulop, A Larbi, G Pawelec, A Khalil, AA Cohen… - Clinical reviews in …, 2021‏ - Springer
The inflammaging concept was introduced in 2000 by Prof. Franceschi. This was an
evolutionary or rather a revolutionary conceptualization of the immune changes in response …

The aging gut microbiome and its impact on host immunity

N Bosco, M Noti - Genes & Immunity, 2021‏ - nature.com
The microbiome plays a fundamental role in the maturation, function, and regulation of the
host-immune system from birth to old age. In return, the immune system has co-evolved a …

[HTML][HTML] Western diet as a trigger of Alzheimer's disease: From metabolic syndrome and systemic inflammation to neuroinflammation and neurodegeneration

A Więckowska-Gacek, A Mietelska-Porowska… - Ageing research …, 2021‏ - Elsevier
An excess of saturated fatty acids and simple sugars in the diet is a known environmental
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …

High-fat, western-style diet, systemic inflammation, and gut microbiota: a narrative review

IJ Malesza, M Malesza, J Walkowiak, N Mussin… - Cells, 2021‏ - mdpi.com
The gut microbiota is responsible for recovering energy from food, providing hosts with
vitamins, and providing a barrier function against exogenous pathogens. In addition, it is …

Nutrition, immunity and COVID-19

PC Calder - BMJ nutrition, prevention & health, 2020‏ - pmc.ncbi.nlm.nih.gov
The immune system protects the host from pathogenic organisms (bacteria, viruses, fungi,
parasites). To deal with this array of threats, the immune system has evolved to include a …

WHO working definition of vitality capacity for healthy longevity monitoring

I Bautmans, V Knoop, JA Thiyagarajan… - The lancet Healthy …, 2022‏ - thelancet.com
Intrinsic capacity, a crucial concept in healthy ageing, is defined by WHO as" the composite
of all the physical and mental capacities that an individual can draw on at any point in time" …

[HTML][HTML] Diet and immune function

CE Childs, PC Calder, EA Miles - Nutrients, 2019‏ - mdpi.com
A well-functioning immune system is critical for survival. The immune system must be
constantly alert, monitoring for signs of invasion or danger. Cells of the immune system must …

Biological Versus Chronological Aging: JACC Focus Seminar

MR Hamczyk, RM Nevado, A Barettino, V Fuster… - Journal of the American …, 2020‏ - jacc.org
Aging is the main risk factor for vascular disease and ensuing cardiovascular and
cerebrovascular events, the leading causes of death worldwide. In a progressively aging …