Astrocyte function from information processing to cognition and cognitive impairment

M Santello, N Toni, A Volterra - Nature neuroscience, 2019 - nature.com
Astrocytes serve important roles that affect recruitment and function of neurons at the local
and network levels. Here we review the contributions of astrocyte signaling to synaptic …

[HTML][HTML] Behaviorally consequential astrocytic regulation of neural circuits

J Nagai, X Yu, T Papouin, E Cheong, MR Freeman… - Neuron, 2021 - cell.com
Astrocytes are a large and diverse population of morphologically complex cells that exist
throughout nervous systems of multiple species. Progress over the last two decades has …

Timing to be precise? An overview of spike timing-dependent plasticity, brain rhythmicity, and glial cells interplay within neuronal circuits

Y Andrade-Talavera, A Fisahn… - Molecular …, 2023 - nature.com
In the mammalian brain information processing and storage rely on the complex coding and
decoding events performed by neuronal networks. These actions are based on the …

Cortical astrocytes independently regulate sleep depth and duration via separate GPCR pathways

TV Vaidyanathan, M Collard, S Yokoyama… - Elife, 2021 - elifesciences.org
Non-rapid eye movement (NREM) sleep, characterized by slow-wave electrophysiological
activity, underlies several critical functions, including learning and memory. However, NREM …

The role of astrocyte structural plasticity in regulating neural circuit function and behavior

O Lawal, FP Ulloa Severino, C Eroglu - Glia, 2022 - Wiley Online Library
Brain circuits undergo substantial structural changes during development, driven by the
formation, stabilization, and elimination of synapses. Synaptic connections continue to …

Astrocyte regulation of neural circuit activity and network states

JF Oliveira, A Araque - Glia, 2022 - Wiley Online Library
Astrocytes are known to influence neuronal activity through different mechanisms, including
the homeostatic control of extracellular levels of ions and neurotransmitters and the …

Functional roles of astrocyte calcium elevations: from synapses to behavior

S Guerra-Gomes, N Sousa, L Pinto… - Frontiers in cellular …, 2018 - frontiersin.org
Astrocytes are fundamental players in the regulation of synaptic transmission and plasticity.
They display unique morphological and phenotypical features that allow to monitor and to …

[HTML][HTML] Dopamine activates astrocytes in prefrontal cortex via α1-adrenergic receptors

S Pittolo, S Yokoyama, DD Willoughby, CR Taylor… - Cell reports, 2022 - cell.com
The prefrontal cortex (PFC) is a hub for cognitive control, and dopamine profoundly
influences its functions. In other brain regions, astrocytes sense diverse neurotransmitters …

Astrocyte regulation of synaptic signaling in psychiatric disorders

A Kruyer, PW Kalivas, MD Scofield - Neuropsychopharmacology, 2023 - nature.com
Over the last 15 years, the field of neuroscience has evolved toward recognizing the critical
role of astroglia in sha** neuronal synaptic activity and along with the pre-and …

Astrocytic modulation of neuronal signalling

SS Purushotham, Y Buskila - Frontiers in Network Physiology, 2023 - frontiersin.org
Neuronal signalling is a key element in neuronal communication and is essential for the
proper functioning of the CNS. Astrocytes, the most prominent glia in the brain play a key …