Hypertriglyceridaemia is a common clinical problem. Epidemiologic and genetic studies
have established that triglyceride-rich lipoproteins (TRL) and their remnants as important …

Omics techniques generate large, multidimensional data that are amenable to analysis by
new informatics approaches alongside conventional statistical methods. Systems theories …

Background: Blood lipids are established risk factors for myocardial infarction (MI), but
uncertainty persists about the relevance of lipids, lipoprotein particles, and circulating …

Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …

Given the limited accuracy of clinically used risk scores such as the Systematic COronary
Risk Evaluation 2 system and the Second Manifestations of ARTerial disease 2 risk scores …

An increased risk of cardiovascular disease, independent of conventional risk factors, is
present even at minor levels of renal impairment and is highest in patients with end-stage …

Diabetes is now a pandemic disease. Moreover, a large number of people with prediabetes
are at risk for develo** frank diabetes worldwide. Both type 1 and type 2 diabetes increase …

Abstract BACKGROUND The European Atherosclerosis Society–European Federation of
Clinical Chemistry and Laboratory Medicine Consensus Panel aims to provide …

Several new or emerging drugs for dyslipidemia owe their existence, in part, to human
genetic evidence, such as observations in families with rare genetic disorders or in …

Aim Our aim was to assess the efficacy and safety of mipomersen through a systematic
review of the literature and a meta-analysis of the available clinical studies. Methods A …