Small molecule metabolites: discovery of biomarkers and therapeutic targets

S Qiu, Y Cai, H Yao, C Lin, Y ** of lipid metabolites using an infrared probe in human-derived model systems
Y Bai, CM Camargo, SMK Glasauer, R Gifford… - Nature …, 2024 - nature.com
Understanding metabolic heterogeneity is the key to uncovering the underlying mechanisms
of metabolic-related diseases. Current metabolic imaging studies suffer from limitations …

Artificial intelligence for biomarker discovery in Alzheimer's disease and dementia

LM Winchester, EL Harshfield, L Shi… - Alzheimer's & …, 2023 - Wiley Online Library
With the increase in large multimodal cohorts and high‐throughput technologies, the
potential for discovering novel biomarkers is no longer limited by data set size. Artificial …

Beyond the average patient: how neuroimaging models can address heterogeneity in dementia

S Verdi, AF Marquand, JM Schott, JH Cole - Brain, 2021 - academic.oup.com
Dementia is a highly heterogeneous condition, with pronounced individual differences in
age of onset, clinical presentation, progression rates and neuropathological hallmarks, even …