Physiology and pathophysiology of human airway mucus
The mucus clearance system is the dominant mechanical host defense system of the human
lung. Mucus is cleared from the lung by cilia and airflow, including both two-phase gas-liquid …
lung. Mucus is cleared from the lung by cilia and airflow, including both two-phase gas-liquid …
[HTML][HTML] Thermal and concentration analysis of two immiscible fluids flowing due to ciliary beating
H Huang, S Shaheen, KS Nisar, MB Arain - Ain Shams Engineering Journal, 2024 - Elsevier
This article explores the flow properties with mass and heat transfer of multilayered flow of
two immiscible fluids (Phan-Thien-Tanner and Jeffrey fluid models) flowing due to ciliary …
two immiscible fluids (Phan-Thien-Tanner and Jeffrey fluid models) flowing due to ciliary …
A mathematical model describing the localization and spread of influenza A virus infection within the human respiratory tract
C Quirouette, NP Younis, MB Reddy… - PLoS computational …, 2020 - journals.plos.org
Within the human respiratory tract (HRT), virus diffuses through the periciliary fluid (PCF)
bathing the epithelium. But virus also undergoes advection: as the mucus layer sitting atop …
bathing the epithelium. But virus also undergoes advection: as the mucus layer sitting atop …
Microscale imaging of cilia-driven fluid flow
BK Huang, MA Choma - Cellular and molecular life sciences, 2015 - Springer
Cilia-driven fluid flow is important for multiple processes in the body, including respiratory
mucus clearance, gamete transport in the oviduct, right–left patterning in the embryonic …
mucus clearance, gamete transport in the oviduct, right–left patterning in the embryonic …
Long wavelength analysis amendment on the cilia beating assisted peristalsis in a tube
M Turkyilmazoglu - Theoretical and Computational Fluid Dynamics, 2025 - Springer
This work delves into the peristaltic rheology of two-wave sinusoidal cilia beating within a
tubular pipe. Cilia movement drives the dynamic phenomenon of peristaltic fluid flow …
tubular pipe. Cilia movement drives the dynamic phenomenon of peristaltic fluid flow …
Mechanisms of cilia-driven transport in the airways in the absence of mucus
S Bermbach, K Weinhold, T Roeder… - American journal of …, 2014 - atsjournals.org
Airway mucus is thought to be required for the clearance of inhaled particles by mucociliary
transport, but this view has recently been challenged. To test if mucus is necessary for cilia …
transport, but this view has recently been challenged. To test if mucus is necessary for cilia …
Mucociliary clearance in mice measured by tracking trans-tracheal fluorescence of nasally aerosolized beads
TD Rogers, LE Ostrowski, A Livraghi-Butrico… - Scientific Reports, 2018 - nature.com
Mucociliary clearance (MCC) is the first line of defense in clearing airways. In genetically
engineered mice, each component of this system (ciliary beat, mucus, airway surface …
engineered mice, each component of this system (ciliary beat, mucus, airway surface …
[HTML][HTML] Heat and concentration analysis of two-layered muco-ciliary third grade fluid flow in human airways
Understanding the mechanisms involved in the movement and clearance of mucus within
the human airways is important from a physiological perspective. A mathematical model of …
the human airways is important from a physiological perspective. A mathematical model of …
Effect of fluid viscosity on the cilia-generated flow on a mouse tracheal lumen
K Kikuchi, T Haga, K Numayama-Tsuruta… - Annals of biomedical …, 2017 - Springer
Mucous flow in a tracheal lumen is generated by the beat motion of ciliated cells to provide a
clearance function by discharging harmful dust particles and viruses. Due to its physiological …
clearance function by discharging harmful dust particles and viruses. Due to its physiological …
Three-dimensional numerical analysis of periciliary liquid layer: Ciliary abnormalities in respiratory diseases
Human pulmonary epithelial cells are protected by two layers of fluid—the outer watery
periciliary liquid layer (PCL) and the uppermost non-Newtonian mucus layer (ML). Aerosols …
periciliary liquid layer (PCL) and the uppermost non-Newtonian mucus layer (ML). Aerosols …