Uses of molecular markers in the phylogenetic studies of various organisms have become
increasingly important in recent times. This review gives an overview of different molecular …

The traditional identification of bacteria on the basis of phenotypic characteristics is
generally not as accurate as identification based on genotypic methods. Comparison of the …

Following the discovery of penicillin, which was inactive against Mycobacterium
tuberculosis, Waksman discovered the first antituberculosis agent, streptomycin, by …

Protein synthesis is one of the major targets in the cell for antibiotics. This review endeavors
to provide a comprehensive “post-ribosome structure” A–Z of the huge diversity of antibiotics …

The crystal structures of six complexes between aminoglycoside antibiotics (neamine,
gentamicin C1A, kanamycin A, ribostamycin, lividomycin A and neomycin B) and …

Ten percent of inherited diseases are caused by premature termination codon (PTC)
mutations that lead to degradation of the mRNA template and to the production of a non …

Although aminoglycosides have been used as antibacterials for decades, their use has
been hindered by their inherent toxicity and the resistance that has emerged to these …

Antibiotic resistance poses a tremendous threat to human health. To overcome this problem,
it is essential to know the mechanism of antibiotic resistance in antibiotic-producing and …

About 11% of all human disease-associated gene lesions are nonsense mutations, resulting
in the introduction of an in-frame premature translation-termination codon (PTC) into the …

We have isolated a multiple-aminoglycoside-resistant Escherichia coli strain, strain ARS3,
and have been the first to identify a novel plasmid-mediated 16S rRNA methyltransferase …