Aetiology of biliary atresia: what is actually known?

C Petersen, M Davenport - Orphanet journal of rare diseases, 2013‏ - Springer
Biliary atresia (BA) is a rare disease of unknown etiology and unpredictable outcome, even
when there has been timely diagnosis and exemplary surgery. It has been the commonest …

Liver fibrosis in biliary atresia

WJ Shen, G Chen, M Wang, S Zheng - world Journal of Pediatrics, 2019‏ - Springer
Background Biliary atresia (BA) is the most common cause of obstructive jaundice in infants.
Although the Kasai procedure has greatly improved the prognosis, most patients still need …

Congenital aflatoxicosis, mal-detoxification genomics & ontogeny trigger immune-mediated Kotb disease biliary atresia variant: SANRA compliant review

MA Kotb, A Kotb, S Talaat, SM Shehata, N El Dessouki… - Medicine, 2022‏ - journals.lww.com
Biliary atresia (BA) is the most common indication for pediatric liver transplantation. We
describe The BA variant: Kotb disease. Liver tissue in the Kotb disease BA is massively …

Cholangiocytes as immune modulators in rotavirus‐induced murine biliary atresia

BH Barnes, RM Tucker, F Wehrmann… - Liver …, 2009‏ - Wiley Online Library
Abstract Background/Aims: Biliary atresia (BA) is a progressive disease characterized by
bile duct inflammation and fibrosis. The aetiology is unknown and may be due to a virus …

Development of liver inflammatory injury in biliary atresia: from basic to clinical research

S Chusilp, F Balsamo, B Li, P Vejchapipat… - Pediatric Surgery …, 2023‏ - Springer
Biliary atresia (BA) is a severe cholangiopathy in infants. It is characterized by inflammatory
fibro-obliteration of the intra-and extrahepatic bile ducts. Although the restoration of bile flow …

Expression of activin A in liver tissue and the outcome of patients with biliary atresia

P Džepina, M Ćorić, M Kovačić Perica… - Frontiers in …, 2024‏ - frontiersin.org
Biliary atresia (BA) is a rare disease of unknown etiology which leads to cirrhosis and death
if left untreated. The standard of care is an early hepatoportoenterostomy (HPE). Long-term …

Review of historical cohort: ursodeoxycholic acid in extrahepatic biliary atresia

MA Kotb - Journal of pediatric surgery, 2008‏ - Elsevier
BACKGROUND: Ursodeoxycholic acid is a bile acid that was found to increase bile flow,
protect hepatocytes, and dissolve gallstones. PURPOSE: The objective of this study is to …

Identification of liver immune microenvironment-related hub genes in liver of biliary atresia

J Zhang, Y Luo, M Feng, Q **a - Frontiers in Pediatrics, 2022‏ - frontiersin.org
Background: Biliary atresia (BA) is one of the most common and fatal abnormalities of
newborns. Increasing evidences indicated that immunology was the critical part of the …

Inhibitive Effects of Nickel Chloride (NiCl2) on Thymocytes

K Tang, H Guo, J Deng, H Cui, X Peng, J Fang… - … Trace Element Research, 2015‏ - Springer
The purpose of this study was to define the inhibitive effects of dietary nickel chloride (NiCl
2) on thymocytes in broilers fed on diets supplemented with 0, 300, 600, and 900 mg/kg of …

Effect of dietary nickel chloride on splenic immune function in broilers

J Huang, H Cui, X Peng, J Fang, Z Zuo, J Deng… - Biological trace element …, 2014‏ - Springer
This study was designed to evaluate the effects of dietary nickel chloride (NiCl 2) on the
splenic immunity in broilers by observing changes of cytokine mRNA expression and protein …