Recent advances on the carboxylations of C (sp3)–H bonds using CO2 as the carbon source

S Pradhan, S Das - Synlett, 2023 - thieme-connect.com
Carbon dioxide (CO 2) is widely known as being a sustainable C1 synthon for the synthesis
of various carboxylic acid derivatives, including essential natural and unnatural amino acids …

Challenges and recent advancements in the synthesis of α, α-disubstituted α-amino acids

Y Zhang, J Vanderghinste, J Wang, S Das - Nature communications, 2024 - nature.com
Abstract α, α-Disubstituted α-amino acids (α-AAs) have improved properties compared to
other types of amino acids. They serve as modifiers of peptide conformation and as …

Recyclable Mesoporous Graphitic Carbon Nitride Catalysts for the Sustainable Photoredox Catalyzed Synthesis of Carbonyl Compounds

K Murugesan, A Sagadevan, L Peng, O Savateev… - ACS …, 2023 - ACS Publications
The conversion of feedstock materials into useful chemical compounds through feasible
processes is highly sought after from both industrial and environmental perspectives. In this …

Direct Benzylic C− H Etherification Enabled by Base‐Promoted Halogen Transfer

KI Bone, TR Puleo, MD Delost, Y Shimizu… - Angewandte …, 2024 - Wiley Online Library
We disclose a benzylic C− H oxidative coupling reaction with alcohols that proceeds through
a synergistic deprotonation, halogenation and substitution sequence. The combination of …

[HTML][HTML] Robust late-stage benzylic C (sp3)–H aminations by using transition metal-free photoredox catalysis

PK Sahoo, Y Zhang, Y Qin, P Ren, R Cauwenbergh… - Journal of …, 2023 - Elsevier
Herein we report a transition metal-free approach for the regioselective functionalization of
benzylic C (sp 3) single bondH bonds in the presence of various heterocyclic amines as …

Combined Photocatalysis and Lewis Acid Catalysis Strategy for the Oxa-Pictet–Spengler Reactions of Ethers

N Tanaka, SR Mitton-Fry, MU Hwang, JL Zhu… - ACS …, 2024 - ACS Publications
Saturated oxygen-containing heterocycles are present in numerous natural products and
biologically active compounds. While the oxa-Pictet–Spengler reaction conventionally …

Photocatalytic regioselective C–H bond functionalizations in arenes

J Hu, S Pradhan, S Waiba, S Das - Chemical Science, 2024 - pubs.rsc.org
The direct functionalization of C–H bonds has revolutionized the field of synthetic organic
chemistry by enabling efficient and atom-economical modification of arenes by avoiding …

Visible-light-driven organocatalytic alkoxylation of benzylic C–H bonds

C Bo, F Chen, Q Bu, ZH Du, M Li, B Dai… - The Journal of Organic …, 2023 - ACS Publications
A variety of strategies for direct alkoxylation of the benzyl C–H bond have been developed
toward the construction of benzyl ethers. The light-induced benzyl C–H bond alkoxylation …

Visible Light Mediated Chemoselective Hydroxylation of Benzylic Methylenes

Z Tan, T Chen, J Zhu, W Luo, D Yu… - The Journal of Organic …, 2024 - ACS Publications
We have developed a metal-free photocatalytic selective hydroxylation of benzylic
methylenes to secondary alcohols. This approach utilizes low-cost eosin Y as photocatalyst …

Transition-metal-free access to benzyl ethers via aerobic cross-dehydrogenative coupling of benzylic C (sp 3)–H bonds with alcohols

X Zhang, W Li, Y Yu, M Luo, H Bai, L Shi, H Li - Green Chemistry, 2024 - pubs.rsc.org
We have developed a practical KOtBu-or KOH-catalyzed aerobic cross-dehydrogenative
coupling of benzylic C (sp3)–H bonds with various alcohols utilizing molecular oxygen as …