Phylloquinone (vitamin K1) and menaquinones (vitamin K2 family) are essential for post-
translational γ-carboxylation of a small number of proteins, including clotting factors. These …

ATP-dependent chromatin-remodeling complexes can reorganize and remodel chromatin
and thereby act as important regulator in various cellular processes. Based on considerable …

Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and
predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of …

Lung cancer is the most common cancer in men and women. This cancer is divided into two
main types, namely non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) …

Background In recent years, mRNA-based vaccines with promising safety and functional
characteristics have gained significant momentum in cancer immunotherapy. However …

Metastasis of cancer is directly related to death in almost all cases, however a lot is yet to be
understood about this process. Despite advancements in the available radiological …

Abstract Talin-1 (TLN1), encoded by the TLN1 gene, is a focal adhesion-related protein
capable of binding various proteins in the cytoskeleton. It is also expressed at high levels in …

Multimodal treatment of cancer is an unstoppable revolution in clinical application. However,
designing a platform that integrates therapeutic modalities with different pharmacokinetic …

New therapeutic approaches that antagonize tumour-promoting phenotypes in lung cancer
are needed to improve patient outcomes. Chromosomal instability (CIN) is a hallmark of lung …

Background: Non–small cell lung cancer (NSCLC) is highly malignant with driver somatic
mutations and genomic instability. Long non-coding RNAs (lncRNAs) play a vital role in …