Measurement of oxygen consumption is a powerful and uniquely informative experimental
technique. It can help identify mitochondrial mechanisms of action following pharmacologic …

Advances in self-organizing cardiac organoids to recapitulate human cardiogenesis have
provided a powerful tool for unveiling human cardiac development, studying cardiovascular …

The fluorescence viewing of mitochondria is commonly performed by MitoTracker, a
lipophilic cationic dye that is taken up by the mitochondria. In this forum, we highlight several …

The metabolic charts memorized in early biochemistry courses, and then later forgotten,
have come back to haunt many immunologists with new recognition of the importance of …

Doxorubicin (DOX) is an effective anticancer agent, but its clinical utility is constrained by
dose‐dependent cardiotoxicity, partly due to cardiomyocyte ferroptosis. However, the …

Macrophages are dynamic immune cells that can adopt several activation states.
Fundamental to these functional activation states is the regulation of cellular metabolic …

Detection of metabolic activity enables us to reveal the inherent metabolic state of cells and
elucidate mechanisms underlying cellular homeostasis and growth. However, a …

Metabolism and mechanics are two key facets of structural and functional processes in cells,
such as growth, proliferation, homeostasis and regeneration. Their reciprocal regulation has …

Prenatal phthalate exposure has previously been linked to the development of autism
spectrum disorder (ASD). However, the underlying biological mechanisms remain unclear …

Adenosine 5′-triphosphate, or ATP, is the primary molecule for storing and transferring
energy in cells. ATP is mainly produced via oxidative phosphorylation in mitochondria, and …