Unraveling the Genetic Landscape of Neurological Disorders: Insights into Pathogenesis, Techniques for Variant Identification, and Therapeutic Approaches
Z Firdaus, X Li - International journal of molecular sciences, 2024 - mdpi.com
Genetic abnormalities play a crucial role in the development of neurodegenerative disorders
(NDDs). Genetic exploration has indeed contributed to unraveling the molecular …
(NDDs). Genetic exploration has indeed contributed to unraveling the molecular …
DNA methylation of imprint control regions associated with Alzheimer's disease in non-Hispanic Blacks and non-Hispanic Whites
Alzheimer's disease (AD) prevalence is twice as high in non-Hispanic Blacks (NHBs) as in
non-Hispanic Whites (NHWs). The objective of this study was to determine whether aberrant …
non-Hispanic Whites (NHWs). The objective of this study was to determine whether aberrant …
Whole Blood DNA Methylation Analysis Reveals Epigenetic Changes Associated with ARSACS
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a rare inherited
condition described worldwide and characterized by a wide spectrum of heterogeneity in …
condition described worldwide and characterized by a wide spectrum of heterogeneity in …
Whole genome methylation sequencing in blood from persons with mild cognitive impairment and dementia due to Alzheimer's disease identifies cognitive status
INTRODUCTION Whole genome methylation sequencing (WGMS) in blood identifies
differential DNA methylation in persons with late‐onset dementia due to Alzheimer's disease …
differential DNA methylation in persons with late‐onset dementia due to Alzheimer's disease …
Insights into the Cell Type-specific Epigenetic Landscape of Alzheimer's Disease: Integrating Genetics, Dna Methylation, And Data Science
TY Eulalio - 2024 - search.proquest.com
This dissertation enriches Alzheimer's disease (AD) research by detailing the influence of
DNA methylation within a complex epigenetic framework using advanced data science …
DNA methylation within a complex epigenetic framework using advanced data science …
Computational analyses of transcriptome and DNA methylation data
M Malonzo - 2024 - aaltodoc.aalto.fi
Transcriptomics and epigenomics, via DNA methylation, both study regulation of gene
expression. Transcriptomics cover both expression of coding genes which lead to protein …
expression. Transcriptomics cover both expression of coding genes which lead to protein …
Unraveling the Role of DNA Modifications in Cell Type-Specific Genome Regulation During Aging
KB Tooley - 2024 - search.proquest.com
DNA modifications, methylation and hydroxymethylation in CG and CH contexts, are central
regulators of genomic organization and cell identity. During development, patterns of DNA …
regulators of genomic organization and cell identity. During development, patterns of DNA …