The molecular biology of susceptibility to post-traumatic stress disorder: highlights of epigenetics and epigenomics

GI Al Jowf, C Snijders, BPF Rutten, L de Nijs… - International journal of …, 2021 - mdpi.com
Exposure to trauma is one of the most important and prevalent risk factors for mental and
physical ill-health. Excessive or prolonged stress exposure increases the risk of a wide …

A decennial review of psychotraumatology: what did we learn and where are we going?

M Olff, A Amstadter, C Armour… - European journal of …, 2019 - Taylor & Francis
On 6 December 2019 we start the 10th year of the European Journal of Psychotraumatogy
(EJPT), a full Open Access journal on psychotrauma. This editorial is part of a special issue …

An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci

MW Logue, MW Miller, EJ Wolf, BR Huber… - Clinical …, 2020 - Springer
Background Previous studies using candidate gene and genome-wide approaches have
identified epigenetic changes in DNA methylation (DNAm) associated with posttraumatic …

[BOOK][B] Children in difficulty: A guide to understanding and hel**

J Elliott, M Place - 2012 - taylorfrancis.com
Written by two leading experts in the field, this welcome third edition of Children in Difficulty:
A guide to understanding and hel** discusses some of the most common, yet …

PTSD is associated with increased DNA methylation across regions of HLA-DPB1 and SPATC1L

S Katrinli, Y Zheng, A Gautam, R Hammamieh… - Brain, behavior, and …, 2021 - Elsevier
Posttraumatic stress disorder (PTSD) is characterized by intrusive thoughts, avoidance,
negative alterations in cognitions and mood, and arousal symptoms that adversely affect …

Genome-wide differentially methylated genes associated with posttraumatic stress disorder and longitudinal change in methylation in rape survivors

J Nöthling, N Abrahams, S Toikumo… - Translational …, 2021 - nature.com
Rape is associated with a high risk for posttraumatic stress disorder (PTSD). DNA
methylation changes may confer risk or protection for PTSD following rape by regulating the …

Cross-species convergence of brain transcriptomic and epigenomic findings in posttraumatic stress disorder: A systematic review

DL Núñez-Rios, JJ Martínez-Magaña… - Complex …, 2023 - karger.com
Introduction: Posttraumatic stress disorder (PTSD) is a complex multifactorial disorder
influenced by the interaction of genetic and environmental factors. Analyses of epigenomic …

Surface Plasmon Resonance Imaging-Based Platform Enables Detection of Single, Site-Specific 5-Methylcytosine Associated with Post-traumatic Stress Disorder …

JM Obliosca, O Vest, D Patel, T Ferguson… - ACS Pharmacology & …, 2025 - ACS Publications
While identification of epigenetic changes in individuals with psychiatric dysfunctions such
as post-traumatic stress disorder (PTSD) is paramount to genomic research, there is no …

Differential DNA methylation is associated with hippocampal abnormalities in pediatric posttraumatic stress disorder

JBM Ensink, TJ Keding, P Henneman… - Biological Psychiatry …, 2021 - Elsevier
Background Recent findings in neuroimaging and epigenetics offer important insights into
brain structures and biological pathways of altered gene expression associated with …

[HTML][HTML] Map** the epigenomic landscape of post-traumatic stress disorder in human cortical neurons

DL Núñez-Ríos, ST Nagamatsu… - medRxiv, 2024 - pmc.ncbi.nlm.nih.gov
Graphical Abstract The study conducted a comprehensive genome-wide analysis of
differential 5mC and 5hmC modifications at both CpG and non-CpG sites in postmortem …