Proprotein convertase subtilisin/kexin type 9 (PCSK9) has evolved as a pivotal enzyme in
lipid metabolism and a revolutionary therapeutic target for hypercholesterolemia and its …

The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased significantly over
the last few decades mirroring the increase in obesity and type II diabetes mellitus. NAFLD …

Background Dual neutralisation of interleukin 17A (IL17A) and interleukin 17F (IL17F) is a
potential novel therapeutic approach in psoriatic arthritis. We assessed bimekizumab, a …

Nutrigenomic DNA reprogramming in different chronic diseases and cancer has been
assessed through the stimulation of gene expression and mRNA synthesis versus DNA …

Introduction Minimal erythema dose (MED) remains a parameter of paramount importance to
orient narrow-band (NB)-UVB phototherapy in psoriatic (PsO) patients. Recently, circadian …

Psoriasis is a chronic inflammatory systemic disease characterized by a wide range of
comorbidities. Respiratory comorbidities are currently poorly characterized and with …

Introduction: Psoriasis is a chronic inflammatory disease with a global prevalence of
approximately 2% and significant psychiatric comorbidity. There is a great deal of existing …

Recently, the mTOR signaling has emerged as an important player in the pathogenesis of
psoriasis. We previously found that 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)-induced …

Atopic dermatitis (AD) and psoriasis are the most common chronic inflammatory skin
disorders, which importantly affect the quality of life of patients who suffer them. Among other …

Psoriasis is a chronic relapsing inflammatory and hyperproliferative skin disease affecting
quality of life. It affects an estimated 8 million Americans and more than 125 million people …