Chemically modified and conjugated antimicrobial peptides against superbugs

W Li, F Separovic, NM O'Brien-Simpson… - Chemical Society …, 2021 - pubs.rsc.org
Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050,
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …

Catheter-associated urinary tract infections: current challenges and future prospects

GT Werneburg - Research and reports in urology, 2022 - Taylor & Francis
Catheter-associated urinary tract infection (CAUTI) is the most common healthcare-
associated infection and cause of secondary bloodstream infections. Despite many …

Biofilms: formation, research models, potential targets, and methods for prevention and treatment

Y Su, JT Yrastorza, M Matis, J Cusick, S Zhao… - Advanced …, 2022 - Wiley Online Library
Due to the continuous rise in biofilm‐related infections, biofilms seriously threaten human
health. The formation of biofilms makes conventional antibiotics ineffective and dampens …

Antimicrobial peptide-based materials: Opportunities and challenges

A Rai, R Ferrão, P Palma, T Patricio… - Journal of Materials …, 2022 - pubs.rsc.org
The multifunctional properties of antimicrobial peptides (AMPs) make them attractive
candidates for the treatment of various diseases. AMPs are considered as alternatives to …

A review of the recent advances in antimicrobial coatings for urinary catheters

P Singha, J Locklin, H Handa - Acta biomaterialia, 2017 - Elsevier
More than 75% of hospital-acquired or nosocomial urinary tract infections are initiated by
urinary catheters, which are used during the treatment of 15–25% of hospitalized patients …

Strategies for antimicrobial peptide coatings on medical devices: A review and regulatory science perspective

M Kazemzadeh-Narbat, H Cheng… - Critical reviews in …, 2021 - Taylor & Francis
Indwelling and implanted medical devices are subject to contamination by microbial
pathogens during surgery, insertion or injection, and ongoing use, often resulting in severe …

Polymer-based coatings with integrated antifouling and bactericidal properties for targeted biomedical applications

D Mitra, ET Kang, KG Neoh - ACS Applied Polymer Materials, 2021 - ACS Publications
One of the most detrimental consequences of surface colonization by bacteria is healthcare-
associated infections (HAIs), which contribute to increased patient mortality and morbidity …

Synthesis, self-assembly, and biomedical applications of antimicrobial peptide–polymer conjugates

H Sun, Y Hong, Y **, Y Zou, J Gao, J Du - Biomacromolecules, 2018 - ACS Publications
Antimicrobial peptides (AMPs) have been attracting much attention due to their excellent
antimicrobial efficiency and low rate in driving antimicrobial resistance (AMR), which has …

Recent advances in antimicrobial polymers: a mini-review

KS Huang, CH Yang, SL Huang, CY Chen… - International journal of …, 2016 - mdpi.com
Human safety and well-being is threatened by microbes causing numerous infectious
diseases resulting in a large number of deaths every year. Despite substantial progress in …

Anti-adhesive antimicrobial peptide coating prevents catheter associated infection in a mouse urinary infection model

K Yu, JCY Lo, M Yan, X Yang, DE Brooks… - Biomaterials, 2017 - Elsevier
Catheter-associated urinary tract infections (CAUTIs) represent one of the most common
hospital acquired infections with significant economic consequences and increased patient …