Zwitterionic biomaterials

Q Li, C Wen, J Yang, X Zhou, Y Zhu, J Zheng… - Chemical …, 2022 - ACS Publications
The term “zwitterionic polymers” refers to polymers that bear a pair of oppositely charged
groups in their repeating units. When these oppositely charged groups are equally …

Harnessing the potential of hydrogels for advanced therapeutic applications: Current achievements and future directions

P Lu, D Ruan, M Huang, M Tian, K Zhu… - Signal transduction and …, 2024 - nature.com
The applications of hydrogels have expanded significantly due to their versatile, highly
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …

Bone repair biomaterials: a perspective from immunomodulation

Y Wang, H Zhang, Y Hu, Y **g… - Advanced Functional …, 2022 - Wiley Online Library
With an increasingly aging society, bone defects and fractures have become significant
threats to human health and quality of life. Currently, autologous and allogeneic bone grafts …

[HTML][HTML] Solid implantable devices for sustained drug delivery

E Magill, S Demartis, E Gavini, AD Permana… - Advanced Drug Delivery …, 2023 - Elsevier
Implantable drug delivery systems (IDDS) are an attractive alternative to conventional drug
administration routes. Oral and injectable drug administration are the most common routes …

Immunomodulatory biomaterials for tissue repair

R Whitaker, B Hernaez-Estrada, RM Hernandez… - Chemical …, 2021 - ACS Publications
All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …

3D bioprinting of collagen to rebuild components of the human heart

A Lee, AR Hudson, DJ Shiwarski, JW Tashman… - Science, 2019 - science.org
Collagen is the primary component of the extracellular matrix in the human body. It has
proved challenging to fabricate collagen scaffolds capable of replicating the structure and …

The surface topography of silicone breast implants mediates the foreign body response in mice, rabbits and humans

JC Doloff, O Veiseh, R de Mezerville, M Sforza… - Nature biomedical …, 2021 - nature.com
Silicone is widely used in chronic implants and is generally perceived to be safe. However,
textured breast implants have been associated with immune-related complications …

Design of biodegradable, implantable devices towards clinical translation

C Li, C Guo, V Fitzpatrick, A Ibrahim… - Nature Reviews …, 2020 - nature.com
Biodegradable materials, including natural and synthetic polymers and hydrolyzable metals,
constitute the main components of temporary, implantable medical devices. Besides the …

Design challenges in polymeric scaffolds for tissue engineering

MI Echeverria Molina, KG Malollari… - … in Bioengineering and …, 2021 - frontiersin.org
Numerous surgical procedures are daily performed worldwide to replace and repair
damaged tissue. Tissue engineering is the field devoted to the regeneration of damaged …

Tailoring materials for modulation of macrophage fate

J Li, X Jiang, H Li, M Gelinsky, Z Gu - Advanced Materials, 2021 - Wiley Online Library
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …