Detection and analysis of chiral molecules as disease biomarkers
The chirality of small metabolic molecules is important in controlling physiological processes
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …
Enhancement of the capabilities of liquid chromatography–mass spectrometry with derivatization: general principles and applications
F Xu, L Zou, Y Liu, Z Zhang… - Mass spectrometry …, 2011 - Wiley Online Library
The integration of liquid chromatography–mass spectrometry (LC–MS) with derivatization is
a relatively new and unique strategy that could add value and could enhance the …
a relatively new and unique strategy that could add value and could enhance the …
Resistance to host antimicrobial peptides mediates resilience of gut commensals during infection and aging in Drosophila
A Arias-Rojas, D Frahm, R Hurwitz… - Proceedings of the …, 2023 - National Acad Sciences
Resilience to short-term perturbations, like inflammation, is a fundamental feature of
microbiota, yet the underlying mechanisms of microbiota resilience are incompletely …
microbiota, yet the underlying mechanisms of microbiota resilience are incompletely …
A sensitive and simple ultra-high-performance-liquid chromatography–tandem mass spectrometry based method for the quantification of d-amino acids in body fluids
WF Visser, NM Verhoeven-Duif, R Ophoff… - … of Chromatography A, 2011 - Elsevier
d-Amino acids are increasingly being recognized as important signaling molecules in
mammals, including humans. d-Serine and d-aspartate are believed to act as signaling …
mammals, including humans. d-Serine and d-aspartate are believed to act as signaling …
Use of Marfey's reagent and analogs for chiral amino acid analysis: assessment and applications to natural products and biological systems
R Bhushan, H Brückner - Journal of Chromatography B, 2011 - Elsevier
The present paper describes an updated knowledge and status on Marfey's reagent (MR), 1-
fluoro-2, 4-dinitrophenyl-5-l-alanine amide (FDNP-l-Ala-NH2). The reagent is used for pre …
fluoro-2, 4-dinitrophenyl-5-l-alanine amide (FDNP-l-Ala-NH2). The reagent is used for pre …
Application of TLC, HPLC and GC methods to the study of amino acid and peptide enantiomers: a review
M Dołowy, A Pyka - Biomedical Chromatography, 2014 - Wiley Online Library
Amino acids are very important organic compounds in nature. The biological activity of
amino acids depends mainly on their stereoisomeric configuration (d‐or l‐). Thus, the …
amino acids depends mainly on their stereoisomeric configuration (d‐or l‐). Thus, the …
Dopamine-modified TiO 2 monolith-assisted LDI MS imaging for simultaneous localization of small metabolites and lipids in mouse brain tissue with enhanced …
Localization of metabolites using multiplexed mass spectrometry imaging (MSI) provides
important chemical information for biological research. In contrast to matrix-assisted laser …
important chemical information for biological research. In contrast to matrix-assisted laser …
Paternal cocaine taking elicits epigenetic remodeling and memory deficits in male progeny
Paternal environmental perturbations including exposure to drugs of abuse can produce
profound effects on the physiology and behavior of offspring via epigenetic modifications …
profound effects on the physiology and behavior of offspring via epigenetic modifications …
Serine lipids of Porphyromonas gingivalis are human and mouse Toll-like receptor 2 ligands
RB Clark, JL Cervantes, MW Maciejewski… - Infection and …, 2013 - Am Soc Microbiol
The total cellular lipids of Porphyromas gingivalis, a known periodontal pathogen, were
previously shown to promote dendritic cell activation and inhibition of osteoblasts through …
previously shown to promote dendritic cell activation and inhibition of osteoblasts through …
Cerebrospinal fluid amino acids glycine, serine, and threonine in nonketotic hyperglycinemia
MA Swanson, K Miller, SP Young… - Journal of Inherited …, 2022 - Wiley Online Library
Nonketotic hyperglycinemia (NKH) is caused by deficient glycine cleavage enzyme activity
and characterized by elevated brain glycine. Metabolism of glycine is connected …
and characterized by elevated brain glycine. Metabolism of glycine is connected …