Mood disorders account for a significant global disease burden, and pharmacological
innovation is needed as existing medications are suboptimal. A wide range of evidence …

Sleep-wake and fasting-feeding are tightly coupled behavioral states that require
coordination between several brain regions. The mammalian lateral hypothalamus (LH) is a …

Aims The molecular mechanism of short‐sleep conditions on cognition remains largely
unknown. This research aimed to investigate associations between short sleep …

The sleep–wake cycle is determined by circadian and sleep homeostatic processes.
However, the molecular impact of these processes and their interaction in different brain cell …

Impaired sleep is a common aspect of aging and often precedes the onset of Alzheimer's
disease. Here, we compare the effects of sleep deprivation in young wild-type mice and their …

Sleep is a vital and evolutionarily conserved process, critical to daily functioning and
homeostatic balance. Losing sleep is inherently stressful and leads to numerous detrimental …

Sleep plays an essential role in all studied animals with a nervous system. However, sleep
deprivation leads to various pathological changes and neurobehavioral problems …

Fundamental differences in excitatory pyramidal cells across cortical areas and species
highlight the implausibility of extrapolation from mouse to primate neurons and cortical …

Sleep research is fundamental to understanding health and well-being, as proper sleep is
essential for maintaining optimal physiological function. Here we present SlumberNet, a …

Aging causes progressive deterioration of daily rhythms in behavioral and metabolic
processes and disruption in the regular sleep-wake cycle. Circadian disruption is directly …