Bioactive Properties, Bioavailability Profiles, and Clinical Evidence of the Potential Benefits of Black Pepper (Piper nigrum) and Red Pepper (Capsicum annum) …

PV Dludla, I Cirilli, F Marcheggiani, S Silvestri… - Molecules, 2023 - mdpi.com
The consumption of food-derived products, including the regular intake of pepper, is
increasingly evaluated for its potential benefits in protecting against diverse metabolic …

Piperine for treating breast cancer: A review of molecular mechanisms, combination with anticancer drugs, and nanosystems

CR Quijia, M Chorilli - Phytotherapy Research, 2022 - Wiley Online Library
Piperine (PIP) is an alkaloid found primarily in Piper longum, and this natural compound has
been shown to exert effects on proliferation and survival against various types of cancer. In …

Characteristics, biological properties and analytical methods of piperine: A review

CR Quijia, M Chorilli - Critical reviews in analytical chemistry, 2020 - Taylor & Francis
Piperine (PIP) is a natural alkaloid isolated from Piper longum L. that presents antioxidant,
anticonvulsant, antimicrobial, neuroprotective, larvicidal, antiparasitic, anticancer effect and …

A review on the bioavailability, bio-efficacies and novel delivery systems for piperine

W Zhang, Q Zheng, M Song, J **ao, Y Cao, Q Huang… - Food & Function, 2021 - pubs.rsc.org
As the major naturally occurring alkaloid in pepper with a pungent taste, piperine is known
for its beneficial biological functions and therapeutic effects. In this work, the bioavailability …

Integrated strategy for the extraction and profiling of bioactive metabolites from Passiflora mollissima seeds combining pressurized-liquid extraction and gas/liquid …

D Ballesteros-Vivas, G Alvarez-Rivera, E Ibánez… - … of Chromatography A, 2019 - Elsevier
An integrated analytical methodology based on pressurized-liquid extraction (PLE) in two
steps, followed by in vitro assays and liquid chromatography/gas chromatography coupled …

A multi-analytical platform based on pressurized-liquid extraction, in vitro assays and liquid chromatography/gas chromatography coupled to high resolution mass …

D Ballesteros-Vivas, G Álvarez-Rivera, E Ibáñez… - … of Chromatography A, 2019 - Elsevier
A multi-analytical strategy for the valorisation of goldenberry calyx, a promising source of
health-promoting compounds, is presented in this work. A comprehensive characterization …

Piperine: Chemical, biological and nanotechnological applications

CR Quijia, VH Araujo, M Chorilli - Acta pharmaceutica, 2021 - hrcak.srce.hr
Sažetak Piperine (PIP) is an alkaloid present in several species of piper, mainly Piper
nigrum Linn. and P. longum, among other species. The present article provides a …

[HTML][HTML] Safety aspects of the use of isolated piperine ingested as a bolus

R Ziegenhagen, K Heimberg, A Lampen… - Foods, 2021 - mdpi.com
Piperine is a natural ingredient of Piper nigrum (black pepper) and some other Piper
species. Compared to the use of pepper for food seasoning, piperine is used in food …

An enhanced strategy integrating offline two-dimensional separation and step-wise precursor ion list-based raster-mass defect filter: Characterization of indole …

H Pan, C Yao, W Yang, S Yao, Y Huang… - … of Chromatography A, 2018 - Elsevier
Comprehensive chemical profiling is of great significance for understanding the therapeutic
material basis and quality control of herbal medicines, which is challenging due to its …

Synergistic enhancement: Exploring the potential of piperine in cancer therapeutics through chemosensitization and combination therapies

MK Manickasamy, A Kumar, B BharathwajChetty… - Life Sciences, 2024 - Elsevier
Despite significant advancements in chemotherapy, effective treatments for advanced
cancer stages remain largely elusive due to chemoresistance. Resistance to anticancer …