In the era of targeted therapy based on genomic alterations, the treatment strategy for
metastatic colorectal cancer (mCRC) has been changing. Before systemic treatment …

(1) Background: Colorectal cancer (CRC) is the third most common cancer and the second
leading cause of cancer-related mortality worldwide. Up to 50% of patients with CRC …

Colorectal cancer (CRC) is the second most common cause of cancer death in the United
States. Every 3 years, the American Cancer Society provides an update of CRC statistics …

Oncologists face increasingly complex clinical decision-making processes as new cancer
therapies are approved and treatment guidelines are revised at an unprecedented rate. With …

Certain genetic alterations and right-sided primary tumor location are associated with
resistance to anti-epidermal growth factor (EGFR) treatment in metastatic colorectal cancer …

Colorectal cancer (CRC) is a prevalent gastrointestinal cancer posing significant clinical
challenges. CRC management traditionally involves surgery, often coupled with …

Liver cancers are the fourth leading cause of cancer-related mortality worldwide. In the past
decade, breakthroughs in the field of artificial intelligence (AI) have inspired development of …

ASCO Guidelines provide recommendations with comprehensive review and analyses of
the relevant literature for each recommendation, following the guideline development …

Current management of locally advanced rectal cancer achieves high cure rates, distant
metastatic spread being the main cause of patients' death. Total neoadjuvant therapy (TNT) …

Background Contemporary management of patients with synchronous colorectal cancer and
liver metastases is complex. The aim of this project was to provide a practical framework for …