Aging is a complex biological process characterized by hallmark features accumulating over
the life course, sha** the individual's aging trajectory and subsequent disease risks. There …

Background It is a well-described clinical phenomenon that females live longer than males,
yet tend to experience greater levels of co-morbidity and disability. Females can therefore be …

The ability to investigate therapeutic interventions in animal models of neurodegenerative
diseases depends on extensive characterization of the model (s) being used. There are …

Introducción La fragilidad es una condición crónica íntimamente relacionada con resultados
de salud. Los índices de fragilidad (IF)–que comparten con la valoración integral geriátrica …

Sarcopenia and frailty are geriatric syndromes characterized by multisystem decline, which
are related to and reflected by markers of skeletal muscle dysfunction. In older people …

Since the last decade, geriatrics and gerontology researchers have been devoting an
increasing amount of efforts in the attempt of designing, develo**, and implementing …

1. Geriatric Medicine, University of Miami Miller School of Medicine, Miami, Florida, USA; 2.
Torrens University of Australia, Adelaide and Baker Heart and Diabetes Institute, Melbourne …

The two most commonly employed frailty measures are the frailty phenotype and the frailty
index. We compared them to examine whether they demonstrated common characteristics of …

OBJECTIVE. The purpose of this article is to review the nomenclature, clinical impact, and
diagnostic techniques characterizing sarcopenia. CONCLUSION. Sarcopenia—defined as …

The notion of frailty has evolved for more than 15 years. Although there is no consensus
definition, frailty reflects a state of increased vulnerability to adverse health outcomes for …