Antidiabetic activity of avocado seeds (Persea americana Mill.) in diabetic rats via activation of PI3K/AKT signaling pathway

OA Ojo, JC Amanze, AI Oni, S Grant, M Iyobhebhe… - Scientific reports, 2022 - nature.com
The treatment of diabetes involves the use of herbal plants, attracting interest in their cost-
effectiveness and efficacy. An aqueous extract of Persea americana seeds (AEPAS) was …

Annona muricata L. peel extract inhibits carbohydrate metabolizing enzymes and reduces pancreatic β-cells, inflammation, and apoptosis via upregulation of PI3K …

OA Ojo, S Grant, JC Amanze, AI Oni, AB Ojo… - Plos one, 2022 - journals.plos.org
Background and objective Annona muricata L. peel has been recognized for many
ethnobotanical uses, including diabetes management. However, limited detailed scientific …

Sterculia tragacantha Lindl Leaf Extract Ameliorates STZ-Induced Diabetes, Oxidative Stress, Inflammation and Neuronal Impairment

AS Onikanni, B Lawal, AO Olusola… - Journal of …, 2021 - Taylor & Francis
Background Sterculia tragacantha is a medicinal plant commonly used in the western part of
Nigeria, for managing diabetes mellitus. However, there is a dearth of scientific information …

Nephroprotective Effect of Hibiscus Sabdariffa Leaf Flavonoid Extracts via KIM-1 and TGF-1β Signaling Pathways in Streptozotocin-Induced Rats

BO Ajiboye, CD Famusiwa, DM Nifemi, BM Ayodele… - ACS …, 2024 - ACS Publications
Diabetes-induced kidney damage represents a substantial health hazard, emphasizing the
imperative to explore potential therapeutic interventions. This study investigates the …

Investigating the role of polyphenols from Pleurospermum candollei (DC.) extract against diabetic nephropathy through modulating inflammatory cytokines and renal …

M Fatima, MR Khan - Journal of Molecular Structure, 2024 - Elsevier
Pleurosepermum candollei is a local vegetable that is traditionally used to cure abdominal
problems, pain, and infertility. The purpose of this study was to evaluate the therapeutic …

Potential effect of Turbinaria decurrens acetone extract on the biochemical and histological parameters of alloxan-induced diabetic rats

OH Abdel-Karim, AM Abo-Shady… - International Journal …, 2022 - Taylor & Francis
Upon Seeking natural and safe alternatives for synthetic medicines to treat many chronic
diseases, seaweeds have offered a promising resource to produce numerous bioactive …

Sterculia tragacantha Lindl aqueous leaf extract ameliorate cardiomyopathy in streptozotocin-induced diabetic rats via urotensin II and FABP3 expressions

BO Ajiboye, BE Oyinloye, SA Onikanni… - Journal of Oleo …, 2021 - jstage.jst.go.jp
Sterculia tragacantha (ST) Lindl leaf is commonly used locally in the management of
diabetes mellitus (DM) and its complications. This study was aimed at assessing the …

Attenuation of diabetic nephropathy in alloxan-induced diabetic rats by Solanum macrocarpon Linn aqueous leaves extract

L Ekakitie, BO Ajiboye, BE Oyinloye… - Comparative Clinical …, 2021 - Springer
Solanum macrocarpon leaf is one of the medicinal plants locally used to manage diabetic
nephropathy. This has been established in scientific studies as one of the main factors …

[PDF][PDF] Potential of Pterocarpus erinaceus aqueous stem bark extract to prevent oxidative kidney damage in diabetic rats

OP Nzute, AU Ijeomah, SO Ajiboso… - Asian J. Res …, 2023 - researchgate.net
Diabetes is a chronic, metabolic disease characterized by elevated levels of blood glucose,
which over time leads to serious damage to the heart, blood vessels, eyes, kidneys and …

Novel ketogenic diet formulation improves sucrose‐induced insulin resistance in canton strain Drosophila melanogaster

OT Kayode, D Rotimi, E Okoh… - Journal of Food …, 2021 - Wiley Online Library
This study investigates the antidiabetic effect of a ketogenic diet (KD) on sucrose‐induced
insulin resistance in the fruit fly model. The fruit flies were divided and grouped into four …