Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics

S Qin, W **ao, C Zhou, Q Pu, X Deng, L Lan… - Signal transduction and …, 2022 - nature.com
Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …

Roles of Two-Component Systems in Pseudomonas aeruginosa Virulence

M Sultan, R Arya, KK Kim - International journal of molecular sciences, 2021 - mdpi.com
Pseudomonas aeruginosa is an opportunistic pathogen that synthesizes and secretes a
wide range of virulence factors. P. aeruginosa poses a potential threat to human health …

Regulation of flagellar motility during biofilm formation

SB Guttenplan, DB Kearns - FEMS microbiology reviews, 2013 - academic.oup.com
Many bacteria swim in liquid or swarm over solid surfaces by synthesizing rotary flagella.
The same bacteria that are motile also commonly form nonmotile multicellular aggregates …

Identification of FleQ from Pseudomonas aeruginosa as ac‐di‐GMP‐responsive transcription factor

JW Hickman, CS Harwood - Molecular microbiology, 2008 - Wiley Online Library
High levels of the intracellular signalling molecule cyclic diguanylate (c‐di‐GMP) supress
motility and activate exopolysaccharide (EPS) production in a variety of bacterial species. In …

The Main Aeromonas Pathogenic Factors

JM Tomás - International Scholarly Research Notices, 2012 - Wiley Online Library
The members of the Aeromonas genus are ubiquitous, water‐borne bacteria. They have
been isolated from marine waters, rivers, lakes, swamps, sediments, chlorine water, water …

Two-component systems required for virulence in Pseudomonas aeruginosa

VI Francis, EC Stevenson, SL Porter - FEMS microbiology letters, 2017 - academic.oup.com
Pseudomonas aeruginosa is a versatile opportunistic pathogen capable of infecting a broad
range of hosts, in addition to thriving in a broad range of environmental conditions outside of …

A signaling network reciprocally regulates genes associated with acute infection and chronic persistence in Pseudomonas aeruginosa

AL Goodman, B Kulasekara, A Rietsch, D Boyd… - Developmental cell, 2004 - cell.com
The opportunistic pathogen Pseudomonas aeruginosa causes a variety of acute and chronic
infections. We identified a gene whose inactivation results in attenuation of virulence due to …

Pseudomonas aeruginosa

W Wu, Y **, F Bai, S ** - Molecular medical microbiology, 2015 - Elsevier
Pseudomonas aeruginosa is a ubiquitous environmental bacterium which causes
opportunistic human infections. A large number of metabolic pathways and regulatory genes …

Bacterial flagellar filament: a supramolecular multifunctional nanostructure

M Nedeljković, DE Sastre, EJ Sundberg - International Journal of …, 2021 - mdpi.com
The bacterial flagellum is a complex and dynamic nanomachine that propels bacteria
through liquids. It consists of a basal body, a hook, and a long filament. The flagellar filament …

The FleQ protein from Pseudomonas aeruginosa functions as both a repressor and an activator to control gene expression from the pel operon promoter in response …

C Baraquet, K Murakami, MR Parsek… - Nucleic acids …, 2012 - academic.oup.com
Abstract Bis-(3′–5′)-cyclic dimeric guanosine monophosphate (c-di-GMP) modulates the
transition between planktonic and biofilm life styles. In response to c-di-GMP, the enhancer …