Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics

S Qin, W **ao, C Zhou, Q Pu, X Deng, L Lan… - Signal transduction and …, 2022 - nature.com
Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …

[HTML][HTML] Roles of Two-Component Systems in Pseudomonas aeruginosa Virulence

M Sultan, R Arya, KK Kim - International journal of molecular sciences, 2021 - mdpi.com
Pseudomonas aeruginosa is an opportunistic pathogen that synthesizes and secretes a
wide range of virulence factors. P. aeruginosa poses a potential threat to human health …

Regulation of flagellar motility during biofilm formation

SB Guttenplan, DB Kearns - FEMS microbiology reviews, 2013 - academic.oup.com
Many bacteria swim in liquid or swarm over solid surfaces by synthesizing rotary flagella.
The same bacteria that are motile also commonly form nonmotile multicellular aggregates …

Pseudomonas aeruginosa Cytotoxins: Mechanisms of Cytotoxicity and Impact on Inflammatory Responses

SJ Wood, JW Goldufsky, MY Seu, AH Dorafshar… - Cells, 2023 - mdpi.com
Pseudomonas aeruginosa is one of the most virulent opportunistic Gram-negative bacterial
pathogens in humans. It causes many acute and chronic infections with morbidity and …

Two-component systems required for virulence in Pseudomonas aeruginosa

VI Francis, EC Stevenson, SL Porter - FEMS microbiology letters, 2017 - academic.oup.com
Pseudomonas aeruginosa is a versatile opportunistic pathogen capable of infecting a broad
range of hosts, in addition to thriving in a broad range of environmental conditions outside of …

The Main Aeromonas Pathogenic Factors

JM Tomás - International Scholarly Research Notices, 2012 - Wiley Online Library
The members of the Aeromonas genus are ubiquitous, water‐borne bacteria. They have
been isolated from marine waters, rivers, lakes, swamps, sediments, chlorine water, water …

Identification of FleQ from Pseudomonas aeruginosa as ac‐di‐GMP‐responsive transcription factor

JW Hickman, CS Harwood - Molecular microbiology, 2008 - Wiley Online Library
High levels of the intracellular signalling molecule cyclic diguanylate (c‐di‐GMP) supress
motility and activate exopolysaccharide (EPS) production in a variety of bacterial species. In …

[HTML][HTML] Two component regulatory systems and antibiotic resistance in Gram-negative pathogens

AY Bhagirath, Y Li, R Patidar, K Yerex, X Ma… - International journal of …, 2019 - mdpi.com
Gram-negative pathogens such as Klebsiella pneumoniae, Acinetobacter baumannii, and
Pseudomonas aeruginosa are the leading cause of nosocomial infections throughout the …

[HTML][HTML] Pseudomonas Flagella: Generalities and Specificities

M Bouteiller, C Dupont, Y Bourigault, X Latour… - International journal of …, 2021 - mdpi.com
Flagella-driven motility is an important trait for bacterial colonization and virulence. Flagella
rotate and propel bacteria in liquid or semi-liquid media to ensure such bacterial fitness …

Contact lens-related corneal infection: Intrinsic resistance and its compromise

SMJ Fleiszig, AR Kroken, V Nieto, MR Grosser… - Progress in retinal and …, 2020 - Elsevier
Contact lenses represent a widely utilized form of vision correction with more than 140
million wearers worldwide. Although generally well-tolerated, contact lenses can cause …