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Pravastatin, proton-pump inhibitors, metformin, micronutrients, and biologics: new horizons for the prevention or treatment of preeclampsia
There has been increasing research momentum to identify new therapeutic agents for the
prevention or treatment of preeclampsia, drugs that can affect the underlying disease …
prevention or treatment of preeclampsia, drugs that can affect the underlying disease …
Translation of mechanistic advances in preeclampsia to the clinic: long and winding road
R Thadhani, AS Cerdeira… - The FASEB Journal, 2024 - Wiley Online Library
As one of the leading causes of premature birth and maternal and infant mortality worldwide,
preeclampsia remains a major unmet public health challenge. Preeclampsia and related …
preeclampsia remains a major unmet public health challenge. Preeclampsia and related …
Novel approaches to combat preeclampsia: from new drugs to innovative delivery
Preeclampsia is a complex disease affecting 2–8% of pregnancies worldwide. It poses
significant risk of maternal and perinatal morbidity and mortality. Despite the rising research …
significant risk of maternal and perinatal morbidity and mortality. Despite the rising research …
Proton pump inhibitors and preeclampsia risk among 157 720 women: a Swedish population register–based cohort study
Preeclampsia is a hypertensive disorder of pregnancy with a high rate of maternal and
neonatal morbidity and mortality. The only definite treatment is delivery. Preclinical …
neonatal morbidity and mortality. The only definite treatment is delivery. Preclinical …
Effects of apelin on neonatal brain neurogenesis in L-NAME-induced maternal preeclampsia
C Tomruk, C Şirin Tomruk, B Denizlioğlu… - Scientific Reports, 2024 - nature.com
The aim of this study was to investigate the possible protective effects of apelin, which is
known to have antioxidant and anti-inflammatory effects, on changes in neurogenesis in …
known to have antioxidant and anti-inflammatory effects, on changes in neurogenesis in …
Novel therapeutic and diagnostic approaches for preeclampsia
We provide an updated framework of the current approaches to define and diagnose
preeclampsia. Disease modifying therapies (in particular, targeting the angiogenic pathway) …
preeclampsia. Disease modifying therapies (in particular, targeting the angiogenic pathway) …
NLRP3 inhibition improves maternal hypertension, inflammation, and vascular dysfunction in response to placental ischemia
X Wang, OK Travis, CA Shields… - American Journal …, 2023 - journals.physiology.org
Preeclampsia (PE) is a pregnancy-specific hypertensive disorder with end-organ damage
that presents after 20 wk of gestation. PE pathophysiology often includes vascular …
that presents after 20 wk of gestation. PE pathophysiology often includes vascular …
[PDF][PDF] Treatment of reflux disease during pregnancy and lactation
Ü Dağlı, İH Kalkan - Turk J Gastroenterol, 2017 - cpdcentre.co.za
Gastroesophageal reflux disease (GERD) is frequently seen during pregnancy. In the
medical treatment of pregnant women with GERD, alginic acid and sucralfate can be used …
medical treatment of pregnant women with GERD, alginic acid and sucralfate can be used …
Receipt of proton-pump inhibitors during pregnancy and risk for preeclampsia
Objective This study aimed to determine whether receiving a proton-pump inhibitor (PPI)
prescription during pregnancy was associated with decreased risk for preeclampsia. Study …
prescription during pregnancy was associated with decreased risk for preeclampsia. Study …
[PDF][PDF] Study Effect of Esomeprazole on the Treatment of Preeclampsia in Pregnant Women: A Double-Blind Clinical Trial Study
Background: Preeclampsia is one of the most serious complications of pregnancy, leading to
various maternal and fetal complications. Objectives: This study aimed to determine the …
various maternal and fetal complications. Objectives: This study aimed to determine the …