Harnessing EHR data for health research

AS Tang, SR Woldemariam, S Miramontes… - Nature Medicine, 2024 - nature.com
With the increasing availability of rich, longitudinal, real-world clinical data recorded in
electronic health records (EHRs) for millions of patients, there is a growing interest in …

[HTML][HTML] How to build the virtual cell with artificial intelligence: Priorities and opportunities

C Bunne, Y Roohani, Y Rosen, A Gupta, X Zhang… - Cell, 2024 - cell.com
Cells are essential to understanding health and disease, yet traditional models fall short of
modeling and simulating their function and behavior. Advances in AI and omics offer …

From virtual patients to digital twins in immuno-oncology: lessons learned from mechanistic quantitative systems pharmacology modeling

H Wang, T Arulraj, A Ippolito, AS Popel - NPJ Digital Medicine, 2024 - nature.com
Virtual patients and digital patients/twins are two similar concepts gaining increasing
attention in health care with goals to accelerate drug development and improve patients' …

Opportunities for use of neuroimaging in de-risking drug development and improving clinical outcomes in psychiatry: an industry perspective

A Etkin, J Powell, AJ Savitz - Neuropsychopharmacology, 2024 - nature.com
Neuroimaging, across positron emission tomography (PET), electroencephalography (EEG),
and magnetic resonance imaging (MRI), has been a mainstay of clinical neuroscience …

AI-driven multi-omics integration for multi-scale predictive modeling of causal genotype-environment-phenotype relationships

Y Wu, L **e - arxiv preprint arxiv:2407.06405, 2024 - arxiv.org
Despite the wealth of single-cell multi-omics data, it remains challenging to predict the
consequences of novel genetic and chemical perturbations in the human body. It requires …

E‐waste: mechanisms of toxicity and safety testing

C Eze, M Vinken - FEBS Open bio, 2024 - Wiley Online Library
Currently, information on the toxicity profile of the majority of the identified e‐waste
chemicals, while extensive and growing, is admittedly fragmentary, particularly at the cellular …

Digital twins in healthcare: Applications, technologies, simulations, and future trends

M Abd Elaziz, MAA Al‐qaness, A Dahou… - … : Data Mining and …, 2024 - Wiley Online Library
The healthcare industry has witnessed significant interest in applying DTs (DTs), due to
technological advancements. DTs are virtual replicas of physical entities that adapt to real …

Unlocking Potential: Proving the Value of Digital Twins to Healthcare Executives

H Joshi, S Joseph, P Shukla - … and Future Directions of Digital Twins …, 2024 - igi-global.com
This chapter explores the effective communication of digital twin technology's value to
healthcare executives. It identifies the critical role that healthcare managers play in …

[HTML][HTML] Applications of Multimodal Artificial Intelligence in Non-Hodgkin Lymphoma B Cells

P Isavand, SS Aghamiri, R Amin - Biomedicines, 2024 - mdpi.com
Given advancements in large-scale data and AI, integrating multimodal artificial intelligence
into cancer research can enhance our understanding of tumor behavior by simultaneously …

Digital twins for chronic lung diseases

A Gonsard, M Genet… - European Respiratory …, 2024 - publications.ersnet.org
Digital twins have recently emerged in healthcare. They combine advances in cyber–
physical systems, modelling and computation techniques, and enable a bidirectional flow of …