Placental transfer of maternal IgG antibodies to the fetus is an important mechanism that
provides protection to the infant while his/her humoral response is inefficient. IgG is the only …

Antibody-dependent cell-mediated cytotoxicity (ADCC) is a potent cytotoxic mechanism that
is mainly mediated in humans by natural killer (NK) cells. ADCC mediates the clinical benefit …

▪ Abstract NK cells are regulated by opposing signals from receptors that activate and inhibit
effector function. While positive stimulation may be initiated by an array of co-stimulatory …

NATURAL KILLER (NK) cells comprise 10% to 15% of human peripheral blood lymphocytes
(PBL) and most have the morphology of large granular lymphocytes (LGL). 1, 2 NK cells are …

A novel polymorphism in the extracellular domain 2 (EC2) of FcgammaRIIIA affects ligand
binding by natural killer (NK) cells and monocytes from genotyped homozygous normal …

A low affinity receptor for IgG immune complexes, Fc gamma RIII (CD16), is expressed on
human NK cells as an integral membrane glycoprotein anchored through a transmembrane …

BACKGROUND: Defects in the development or activation of T cells result in
immunodeficiency associated with severe infections early in life. T-cell activation requires …

Immunoglobulin-like transcript (ILT) 3 is a novel cell surface molecule of the immunoglobulin
superfamily, which is selectively expressed by myeloid antigen presenting cells (APCs) such …

NATURAL killer (NK) cells are a subset of lymphocytes that mediate major histocompatibility
complex (MHC)-nonrestricted cytotoxicity against tumours and virus-infected cells and …

Transplacental transport of maternal immunoglobulin G (IgG) to the develo** fetus is
extremely important in the protection of the newborn from infection. Although the exact …