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Regulatory T cells in the treatment of disease
Regulatory T (Treg) cells suppress inflammation and regulate immune system activity. In
patients with systemic or organ-specific autoimmune diseases or those receiving …
patients with systemic or organ-specific autoimmune diseases or those receiving …
Roles of cytokines and T cells in the pathogenesis of myasthenia gravis
Myasthenia gravis (MG) is characterized by muscle weakness and fatigue caused by the
presence of autoantibodies against the acetylcholine receptor (AChR) or the muscle-specific …
presence of autoantibodies against the acetylcholine receptor (AChR) or the muscle-specific …
Vitamin D3 inhibits the proliferation of T helper cells, downregulate CD4+ T cell cytokines and upregulate inhibitory markers
Abstract 1 α, 25-dihydroxyvitamin D3 (VitD3) has been suggested to have strong modulatory
properties in the immune system. Researchers in the present study primarily aimed to …
properties in the immune system. Researchers in the present study primarily aimed to …
Advances in autoimmune myasthenia gravis management
S Wang, I Breskovska, S Gandhy… - Expert review of …, 2018 - Taylor & Francis
Introduction: Myasthenia gravis (MG) is an autoimmune neuromuscular disorder with no
cure and conventional treatments limited by significant adverse effects and variable benefit …
cure and conventional treatments limited by significant adverse effects and variable benefit …
Immunopathogenesis in myasthenia gravis and neuromyelitis optica
Z Wang, Y Yan - Frontiers in immunology, 2017 - frontiersin.org
Myasthenia gravis (MG) and neuromyelitis optica (NMO) are autoimmune channelopathies
of the peripheral neuromuscular junction (NMJ) and central nervous system (CNS) that are …
of the peripheral neuromuscular junction (NMJ) and central nervous system (CNS) that are …
An imbalance between regulatory T cells and T helper 17 cells in acetylcholine receptor–positive myasthenia gravis patients
JA Villegas, J Van Wassenhove… - Annals of the new …, 2018 - Wiley Online Library
A chronic autoimmune disease, myasthenia gravis (MG) is characterized in 85% of patients
by antibodies directed against the acetylcholine receptor (AChR) located at the …
by antibodies directed against the acetylcholine receptor (AChR) located at the …
Causal effect of vitamin D on myasthenia gravis: A two-sample Mendelian randomization study
Y Fan, H Huang, X Chen, Y Chen, X Zeng, F Lin… - Frontiers in …, 2023 - frontiersin.org
Introduction Observational studies suggest that vitamin D supplementation may be effective
in preventing myasthenia gravis (MG). However, the causal relationship between circulating …
in preventing myasthenia gravis (MG). However, the causal relationship between circulating …
Moderate exercise enhances the production of interferon-γ and interleukin-12 in peripheral blood mononuclear cells
The purpose of this study was to explore the effect of two months moderate exercise on
levels of IFN-γ, IL-12, IL-6 and IL-4 in serum and supernatants of in vitro mitogen-activated …
levels of IFN-γ, IL-12, IL-6 and IL-4 in serum and supernatants of in vitro mitogen-activated …
Estrogen receptor, inflammatory, and FOXO transcription factors regulate expression of myasthenia gravis-associated circulating microRNAs
MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate important
intracellular biological processes. In myasthenia gravis (MG), a disease-specific pattern of …
intracellular biological processes. In myasthenia gravis (MG), a disease-specific pattern of …
Decreased regulatory function of CD4+CD25+CD45RA+ T cells and impaired IL‐2 signalling pathway in patients with type 2 diabetes mellitus
V Sheikh, A Zamani… - Scandinavian …, 2018 - Wiley Online Library
In this study, the frequency and function of CD4+ CD25+ CD45RA+ regulatory T cells (Treg)
and intracellular IL‐2 signalling molecules in patients with type 2 diabetes mellitus (T2DM) …
and intracellular IL‐2 signalling molecules in patients with type 2 diabetes mellitus (T2DM) …