The neuropsychological profile of Alzheimer disease

S Weintraub, AH Wicklund… - Cold Spring …, 2012‏ - perspectivesinmedicine.cshlp.org
Neuropsychological assessment has featured prominently over the past 30 years in the
characterization of dementia associated with Alzheimer disease (AD). Clinical …

Imaging and fluid biomarkers in frontotemporal dementia

LH Meeter, LD Kaat, JD Rohrer… - Nature Reviews …, 2017‏ - nature.com
Frontotemporal dementia (FTD), the second most common type of presenile dementia, is a
heterogeneous neurodegenerative disease characterized by progressive behavioural …

Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

AL Young, RV Marinescu, NP Oxtoby… - Nature …, 2018‏ - nature.com
The heterogeneity of neurodegenerative diseases is a key confound to disease
understanding and treatment development, as study cohorts typically include multiple …

Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia

K Rascovsky, JR Hodges, D Knopman, MF Mendez… - Brain, 2011‏ - academic.oup.com
Based on the recent literature and collective experience, an international consortium
developed revised guidelines for the diagnosis of behavioural variant frontotemporal …

Clinical, genetic and pathological heterogeneity of frontotemporal dementia: a review

H Seelaar, JD Rohrer, YAL Pijnenburg… - Journal of Neurology …, 2011‏ - jnnp.bmj.com
Frontotemporal dementia (FTD) is the second most common young-onset dementia and is
clinically characterised by progressive behavioural change, executive dysfunction and …

Behavioural-variant frontotemporal dementia: diagnosis, clinical staging, and management

O Piguet, M Hornberger, E Mioshi… - The Lancet …, 2011‏ - thelancet.com
Patients with behavioural-variant frontotemporal dementia (bvFTD) present with insidious
changes in personality and interpersonal conduct that indicate progressive disintegration of …

Characterizing a neurodegenerative syndrome: primary progressive apraxia of speech

KA Josephs, JR Duffy, EA Strand, MM Machulda… - Brain, 2012‏ - academic.oup.com
Apraxia of speech is a disorder of speech motor planning and/or programming that is
distinguishable from aphasia and dysarthria. It most commonly results from vascular insults …

[HTML][HTML] Interoception primes emotional processing: multimodal evidence from neurodegeneration

PC Salamone, A Legaz, L Sedeño… - Journal of …, 2021‏ - jneurosci.org
Recent frameworks in cognitive neuroscience and behavioral neurology underscore
interoceptive priors as core modulators of negative emotions. However, the field lacks …

Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics

JL Whitwell, SD Weigand, BF Boeve, ML Senjem… - Brain, 2012‏ - academic.oup.com
A major recent discovery was the identification of an expansion of a non-coding GGGGCC
hexanucleotide repeat in the C9ORF72 gene in patients with frontotemporal dementia and …

Clinical and neuroanatomical signatures of tissue pathology in frontotemporal lobar degeneration

JD Rohrer, T Lashley, JM Schott, JE Warren, S Mead… - Brain, 2011‏ - academic.oup.com
Relating clinical symptoms to neuroanatomical profiles of brain damage and ultimately to
tissue pathology is a key challenge in the field of neurodegenerative disease and …