[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: current status and future perspectives

H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced drug delivery …, 2023‏ - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

Advancements and challenges of nanostructured lipid carriers for wound healing applications

N Wathoni, C Suhandi, KM Elamin… - International journal …, 2024‏ - Taylor & Francis
The current treatments for wound healing still exhibit drawbacks due to limited availability at
the action sites, susceptibility to degradation, and immediate drug release, all of which are …

Recent progress of solid lipid nanoparticles and nanostructured lipid carriers as ocular drug delivery platforms

V Gugleva, V Andonova - Pharmaceuticals, 2023‏ - mdpi.com
Sufficient ocular bioavailability is often considered a challenge by the researchers, due to
the complex structure of the eye and its protective physiological mechanisms. In addition, the …

Recent developments of nanostructures for the ocular delivery of natural compounds

MS Razavi, P Ebrahimnejad, Y Fatahi… - Frontiers in …, 2022‏ - frontiersin.org
Ocular disorders comprising various diseases of the anterior and posterior segments are
considered as the main reasons for blindness. Natural products have been identified as …

Sirolimus loaded chitosan functionalized poly (lactic-co-glycolic acid)(PLGA) nanoparticles for potential treatment of age-related macular degeneration

R Suri, YR Neupane, N Mehra, M Nematullah… - International journal of …, 2021‏ - Elsevier
The usefulness of sirolimus (SIR) in the treatment of diseases that involve retinal
degeneration like age-related macular degeneration (AMD) has been well documented …

Nanophyto-gel against multi-drug resistant Pseudomonas aeruginosa burn wound infection

MM Wen, IA Abdelwahab, RG Aly, SA El-Zahaby - Drug Delivery, 2021‏ - Taylor & Francis
Burn wound is usually associated by antibiotic-resistant Pseudomonas aeruginosa infection
that worsens and complicates its management. An effective approach is to use natural …

[HTML][HTML] The potential benefits of polyphenols for corneal diseases

J Feng, Y Zhang - Biomedicine & Pharmacotherapy, 2023‏ - Elsevier
The cornea functions as the primary barrier of the ocular surface, regulating temperature and
humidity while providing protection against oxidative stress, harmful stimuli and pathogenic …

Rapamycin-loaded nanostructured lipid carrier modified with folic acid intended for breast cancer therapy

CF Rodero, MT Luiz, MR Sato, F Boni… - International Journal of …, 2025‏ - Elsevier
Breast cancer stands as the most common form of malignancy among women globally, and
it showcases commendable rates of cure when detected in early-stage and non-metastatic …

Research progress of ophthalmic preparations of immunosuppressants

Y Liu, H Xu, N Yan, Z Tang, Q Wang - Drug Delivery, 2023‏ - Taylor & Francis
Immune ophthalmopathy is a collection of autoimmune eye diseases. Immunosuppressants
are drugs that can inhibit the body's immune response. Considering drug side effects such …

Transferrin decorated-nanostructured lipid carriers (NLCs) are a promising delivery system for rapamycin in Alzheimer's disease: An in vivo study

F Khonsari, M Heydari, M Sharifzadeh, H Valizadeh… - Biomaterials …, 2022‏ - Elsevier
Abstract Alzheimer's disease (AD), the most common neurodegenerative disorder, is
characterized by progressive cognitive impairment and memory loss. The mammalian target …