Healthcare is under increasing demand pressure as societies age and expectations rise,
multiplied by increasing incidence of chronic diseases and decreasing available funding …

Positive end-expiratory pressure results in a sustained positive intrathoracic pressure, which
exerts pressure on intrathoracic vessels, resulting in cardiopulmonary interactions. This …

Abstract Background and Objective Model-based and personalised decision support
systems are emerging to guide mechanical ventilation (MV) treatment for respiratory failure …

Mechanical ventilation (MV) provides respiratory support for critically ill patients in the
intensive care unit (ICU). Waveform data output by the ventilator provides valuable …

This paper presents a novel, mechanics-based framework to create digital twins for
earthquake-affected pinched structures, like reinforced concrete framed buildings. It uses …

Background Optimal setting of mechanical ventilators is critical for improving outcomes.
Accurate, predictive lung mechanics models are effective in optimizing MV settings, but only …

Abstract Background and Objective Mechanical ventilation is the primary form of care
provided to respiratory failure patients. Limited guidelines and conflicting results from major …

Mechanical ventilation is well known for having detrimental effects on the cardiovascular
system, particularly when using high positive end-expiratory pressure. High positive end …

Background and objective Patient-ventilator asynchrony (PVA) is associated with poor
clinical outcomes and remains under-monitored. Automated PVA detection would enable …

Background Patient–ventilator asynchrony is common during mechanical ventilation (MV) in
intensive care unit (ICU), leading to worse MV care outcome. Identification of asynchrony is …