As a systemic autoimmune disease, rheumatoid arthritis (RA) usually causes damage not
only to joints, but also to other tissues and organs including the heart, kidneys, lungs …

Systemic lupus erythematosus (SLE) often features extensive cardiovascular (CV)
comorbidity and patients with SLE are at significantly increased risk of CV event occurrence …

Augmented T cell function leading to host damage in autoimmunity is supported by
metabolic dysregulation, making targeting immunometabolism an attractive therapeutic …

T cells play a critical role in the adaptive immune response of the body, especially against
intracellular pathogens and cancer. In vitro, T cell activation studies typically employ planar …

Cardiovascular diseases (CVDs) are the main contributors to global morbidity and mortality.
Major pathogenic phenotypes of CVDs include the development of endothelial dysfunction …

The prevalence of neurological conditions which manifest with chronic pain is increasing
globally, where the World Health Organisation has now classified chronic pain as a risk …

Systemic lupus erythematosus (SLE) is an auto-immune disease of a relapsing-remitting
nature that can cause multiorgan damage depending on several factors, mainly the disease …

Obesity is associated with impaired immune function, characterized by inflammation, and
leading to poor response to infection, impaired vaccine response, increased susceptibility to …

The prevalence of major depressive disorder (MDD) is highest in young adulthood, an effect
that has been magnified by the COVID-19 pandemic. Importantly, individuals with MDD are …

Background & objectives This study aimed to: 1) analyze the inflammatory profile of
Rheumatoid Arthritis (RA) patients, identifying clinical phenotypes associated with …