Respiratory sequelae of COVID-19: pulmonary and extrapulmonary origins, and approaches to clinical care and rehabilitation
Although the exact prevalence of post-COVID-19 condition (also known as long COVID) is
unknown, more than a third of patients with COVID-19 develop symptoms that persist for …
unknown, more than a third of patients with COVID-19 develop symptoms that persist for …
Idiopathic pulmonary fibrosis (IPF): an overview
Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterised by chronic,
progressive scarring of the lungs and the pathological hallmark of usual interstitial …
progressive scarring of the lungs and the pathological hallmark of usual interstitial …
Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk
Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and
predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of …
predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of …
Senescence of alveolar type 2 cells drives progressive pulmonary fibrosis
Rationale: Idiopathic pulmonary fibrosis (IPF) is an insidious and fatal interstitial lung
disease associated with declining pulmonary function. Accelerated aging, loss of epithelial …
disease associated with declining pulmonary function. Accelerated aging, loss of epithelial …
TGF-β-induced endothelial-mesenchymal transition in fibrotic diseases
E Pardali, G Sanchez-Duffhues… - International journal of …, 2017 - mdpi.com
Fibrotic diseases are characterized by net accumulation of extracellular matrix proteins in
affected organs leading to their dysfunction and ultimate failure. Myofibroblasts have been …
affected organs leading to their dysfunction and ultimate failure. Myofibroblasts have been …
[HTML][HTML] The extracellular matrix and transforming growth factor-β1: Tale of a strained relationship
B Hinz - Matrix biology, 2015 - Elsevier
Physiological tissue repair aims at restoring the mechano-protective properties of the
extracellular matrix. Consequently, redundant regulatory mechanisms are in place ensuring …
extracellular matrix. Consequently, redundant regulatory mechanisms are in place ensuring …
Myofibroblasts
B Hinz - Experimental eye research, 2016 - Elsevier
Myofibroblasts are activated in response to tissue injury with the primary task to repair lost or
damaged extracellular matrix. Enhanced collagen secretion and subsequent contraction …
damaged extracellular matrix. Enhanced collagen secretion and subsequent contraction …
The role of myofibroblasts in wound healing
B Hinz - Current research in translational medicine, 2016 - Elsevier
The importance of proper skin wound healing becomes evident when our body's repair
mechanisms fail, leading to either non-healing (chronic) wounds or excessive repair …
mechanisms fail, leading to either non-healing (chronic) wounds or excessive repair …
Idiopathic pulmonary fibrosis: Epithelial-mesenchymal interactions and emerging therapeutic targets
Idiopathic pulmonary fibrosis (IPF) is a chronic fibrotic disease of the lung that is marked by
progressive decline in pulmonary function and ultimately respiratory failure. Genetic and …
progressive decline in pulmonary function and ultimately respiratory failure. Genetic and …
Particulate matter air pollution and respiratory impact on humans and animals
C Losacco, A Perillo - Environmental Science and Pollution Research, 2018 - Springer
Air pollution is now fully acknowledged to be a public health problem and a social issue.
Particulate matter (PM) concentration has been linked with several clinical manifestations of …
Particulate matter (PM) concentration has been linked with several clinical manifestations of …