Interchromosomal interactions: A genomic love story of kissing chromosomes

PG Maass, AR Barutcu, JL Rinn - Journal of Cell Biology, 2019 - rupress.org
Nuclei require a precise three-and four-dimensional organization of DNA to establish cell-
specific gene-expression programs. Underscoring the importance of DNA topology …

LIM homeodomain proteins and associated partners: Then and now

Y Yasuoka, M Taira - Current topics in developmental biology, 2021 - Elsevier
The field of molecular embryology started around 1990 by identifying new genes and
analyzing their functions in early vertebrate embryogenesis. Those genes encode …

Cell type-specific interchromosomal interactions as a mechanism for transcriptional diversity

A Horta, K Monahan, E Bashkirova, S Lomvardas - bioRxiv, 2018 - biorxiv.org
The eukaryotic genome is partitioned into topologically associated domains (TADs) that
assemble into compartments of shared chromatin valance. This architecture is influenced by …

Antisense lncRNA transcription drives stochastic Protocadherin α promoter choice

D Canzio, CL Nwakeze, A Horta, SM Rajkumar… - bioRxiv, 2018 - biorxiv.org
Stochastic and combinatorial activation of clustered Protocadherin (Pcdh) α, β, and γ gene
promoters generates a cell-surface identity code in individual neurons that functions in …

The 3D genome: investigating the role of Pcf11 and Pol II gene loops in mammalian cell lines

M Perdiou - 2022 - wrap.warwick.ac.uk
Eukaryotic transcription, from initiation to termination, is a highly complex and regulated
process involving the interplay of different factors. Termination is a key step in gene …