Mechanism of testicular injury induced by Di-ethylhexyl phthalate and its protective agents

Y Lin, W Xu, L Yang, Z Chen, J Zhai, Z Guo… - Chemico-Biological …, 2023 - Elsevier
Di-ethylhexyl phthalate (DEHP) is used as an important plasticizer in a wide range of
products such as paints, food packaging, medical devices and children's toys. In recent …

Pioglitazone ameliorates cisplatin-induced testicular toxicity by attenuating oxidative stress and inflammation via TLR4/MyD88/NF-κB signaling pathway

S Hussein, GAM Kamel - Journal of Trace Elements in Medicine and …, 2023 - Elsevier
Background Cisplatin (CIS) is a chemotherapeutic agent widely used to cure several
cancers. It exerts detrimental cellular effects that restrain its clinical application as an …

Attenuative effect of astilbin on polystyrene microplastics induced testicular damage: Biochemical, spermatological and histopathological-based evidences

A Rizwan, MU Ijaz, A Hamza, H Anwar - Toxicology and Applied …, 2023 - Elsevier
Polystyrene microplastics (PS-MPs) are the potential environmental pollutants that possess
the ability to induce testicular damage. Astilbin (ASB) is a dihydroflavonol, abundantly …

The potential protective effect of melatonin and N-acetylcysteine alone and in combination on opioid-induced testicular dysfunction and degeneration in rat

N Mohammadi, S Shirian, A Gorji… - Reproductive …, 2023 - Elsevier
Methadone (Met) is the most common treatment for opioid addiction. Although Met is
effective for treatment of opioid dependence, sexual dysfunctions and infertility have been …

Pioglitazone enhances brain mitochondrial biogenesis and phase II detoxification capacity in neonatal rats with 6-OHDA-induced unilateral striatal lesions

D Vázquez-González, JC Corona - Frontiers in Neuroscience, 2023 - frontiersin.org
The psychostimulant methylphenidate (MPH) is the first-line pharmacological treatment for
attention-deficit/hyperactivity disorder (ADHD), but has numerous adverse side effects. The …

Rosiglitazone attenuates amyloid beta and glial fibrillary acidic protein in the hippocampus and neuroinflammation associated learning and memory impairments in …

F Beheshti, M Hosseini… - Behavioural Brain …, 2023 - Elsevier
Objective The aim of the current study was to investigate the beneficial effects of
rosiglitazone (Rosi) on amyloid beta (Aβ) and glial fibrillary acidic protein (GFAP) in the …

Hypogonadism and nonalcoholic fatty liver disease

K Papadimitriou, AC Mousiolis, G Mintziori… - Endocrine, 2024 - Springer
Nonalcoholic fatty liver disease (NAFLD), recently proposed to be renamed to metabolic
dysfunction-associated steatotic liver disease (MASLD), is a major global public health …

Reprotoxic effect of tris (2, 3-dibromopropyl) isocyanurate (TBC) on spermatogenic cells in vitro

A Tabęcka-Łonczyńska, B Skóra, E Kaleniuk… - Molecules, 2023 - mdpi.com
Tris (2, 3-dibromopropyl) isocyanurate (TBC) belongs to the class of novel brominated flame
retardants (NFBRs) that are widely used in industry. It has commonly been found in the …

Histochemical and histomorphological evidence of the modulating role of 1-isothiocyanate-4-methyl sulfonyl butane on cisplatin-induced testicular-pituitary axis …

SA Adelakun, OW Akintunde, B Ogunlade… - Morphologie, 2023 - Elsevier
Background This study examine the histochemical and histomorphological effect of 1-
isothiocyanato-4-methyl sulfonyl butane (SFN) on cisplatin (CP) induced testicular alteration …

MLN-4760 Induces Oxidative Stress without Blood Pressure and Behavioural Alterations in SHRs: Roles of Nfe2l2 Gene, Nitric Oxide and Hydrogen Sulfide

M Kluknavsky, A Micurova, M Cebova, E Şaman… - Antioxidants, 2022 - mdpi.com
Reduced angiotensin 1–7 bioavailability due to inhibition of angiotensin-converting enzyme
2 (ACE2) may contribute to increased mortality in hypertensive individuals during COVID-19 …