Guidance for the practical management of the direct oral anticoagulants (DOACs) in VTE treatment

AE Burnett, CE Mahan, SR Vazquez, LB Oertel… - Journal of thrombosis …, 2016 - Springer
Venous thromboembolism (VTE) is a serious medical condition associated with significant
morbidity and mortality, and an incidence that is expected to double in the next forty years …

Management of adverse events associated with tyrosine kinase inhibitors: improving outcomes for patients with hepatocellular carcinoma

L Rimassa, R Danesi, T Pressiani, P Merle - Cancer Treatment Reviews, 2019 - Elsevier
Hepatocellular carcinoma (HCC) is the most common form of primary liver cancer.
Sorafenib, regorafenib, lenvatinib and cabozantinib are tyrosine kinase inhibitors (TKIs) that …

EASL Clinical Practice Guidelines on prevention and management of bleeding and thrombosis in patients with cirrhosis

E Villa, M Bianchini, A Blasi, A Denys, EG Giannini… - Journal of …, 2022 - Elsevier
The prevention and management of bleeding and thrombosis in patients with cirrhosis
poses several difficult clinical questions. These Clinical Practice Guidelines have been …

JCS/JHRS 2020 guideline on pharmacotherapy of cardiac arrhythmias

K Ono, Y Iwasaki, M Akao, T Ikeda, K Ishii… - Circulation …, 2022 - jstage.jst.go.jp
The Japanese Circulation Society (JCS) published the “Guidelines for Pharmacological
Treatment of Arrhythmia” in 2004, and a revised edition was published in 2009. 1 Both …

Cardio-oncology drug interactions: a scientific statement from the American Heart Association

CJ Beavers, JE Rodgers, AJ Bagnola, TM Beckie… - Circulation, 2022 - Am Heart Assoc
In the cardio-oncology population, drug interactions are of particular importance given the
complex pharmacological profile, narrow therapeutic index, and inherent risk of therapies …

Recommendations for management of clinically significant drug-drug interactions with statins and select agents used in patients with cardiovascular disease: a …

BS Wiggins, JJ Saseen, RL Page, BN Reed, K Sneed… - Circulation, 2016 - Am Heart Assoc
A n D GUID eLIneS affordability may often dictate which medications may be prescribed.
Patients who have exhausted prescription drug coverage or who are uninsured may require …

Drug delivery challenges in brain disorders across the blood–brain barrier: novel methods and future considerations for improved therapy

A Achar, R Myers, C Ghosh - Biomedicines, 2021 - mdpi.com
Due to the physiological and structural properties of the blood–brain barrier (BBB), the
delivery of drugs to the brain poses a unique challenge in patients with central nervous …

Anticoagulation Strategies in Patients With Cancer: JACC Review Topic of the Week

RC Mosarla, M Vaduganathan, A Qamar… - Journal of the American …, 2019 - jacc.org
Patients with active cancer are at an increased risk of arterial and venous thromboembolism
(VTE) and bleeding events. Historically, in patients with cancer, low molecular weight …

Drug–drug–gene interactions and adverse drug reactions

MA Malki, ER Pearson - The pharmacogenomics journal, 2020 - nature.com
The economic and health burden caused by adverse drug reactions has increased
dramatically in the last few years. This is likely to be mediated by increasing polypharmacy …

The therapeutic importance of acid-base balance

BN Quade, MD Parker, R Occhipinti - Biochemical pharmacology, 2021 - Elsevier
Baking soda and vinegar have been used as home remedies for generations and today we
are only a mouse-click away from claims that baking soda, lemon juice, and apple cider …