[HTML][HTML] Advances in understanding N-glycosylation structure, function, and regulation in health and disease
S Esmail, MF Manolson - European journal of cell biology, 2021 - Elsevier
N-linked glycosylation is a post-translational modification crucial for membrane protein
folding, stability and other cellular functions. Alteration of membrane protein N-glycans is …
folding, stability and other cellular functions. Alteration of membrane protein N-glycans is …
A review of progress in single particle tracking: from methods to biophysical insights
Optical microscopy has for centuries been a key tool to study living cells with minimum
invasiveness. The advent of single molecule techniques over the past two decades has …
invasiveness. The advent of single molecule techniques over the past two decades has …
[HTML][HTML] Eradication of triple-negative breast cancer cells by targeting glycosylated PD-L1
Protein glycosylation provides proteomic diversity in regulating protein localization, stability,
and activity; it remains largely unknown whether the sugar moiety contributes to …
and activity; it remains largely unknown whether the sugar moiety contributes to …
Nanoclustering as a dominant feature of plasma membrane organization
Early studies have revealed that some mammalian plasma membrane proteins exist in small
nanoclusters. The advent of super-resolution microscopy has corroborated and extended …
nanoclusters. The advent of super-resolution microscopy has corroborated and extended …
Weak ergodicity breaking of receptor motion in living cells stemming from random diffusivity
Molecular transport in living systems regulates numerous processes underlying biological
function. Although many cellular components exhibit anomalous diffusion, only recently has …
function. Although many cellular components exhibit anomalous diffusion, only recently has …
Dynamic plasma membrane organization: a complex symphony
S van Deventer, AB Arp, AB van Spriel - Trends in Cell Biology, 2021 - cell.com
Membrane protein organization is essential for proper cellular functioning and the result of a
dynamic exchange between protein monomers, nanoscale protein clusters, and microscale …
dynamic exchange between protein monomers, nanoscale protein clusters, and microscale …
A DNA origami platform for quantifying protein copy number in super-resolution
Single-molecule-based super-resolution microscopy offers researchers a unique opportunity
to quantify protein copy number with nanoscale resolution. However, while fluorescent …
to quantify protein copy number with nanoscale resolution. However, while fluorescent …
Stochastic particle unbinding modulates growth dynamics and size of transcription factor condensates in living cells
G Muñoz-Gil, C Romero-Aristizabal… - Proceedings of the …, 2022 - National Acad Sciences
Liquid–liquid phase separation (LLPS) is emerging as a key physical principle for biological
organization inside living cells, forming condensates that play important regulatory roles …
organization inside living cells, forming condensates that play important regulatory roles …
Mechanisms underlying anomalous diffusion in the plasma membrane
D Krapf - Current topics in membranes, 2015 - Elsevier
The plasma membrane is a complex fluid where lipids and proteins undergo diffusive motion
critical to biochemical reactions. Through quantitative imaging analyses such as single …
critical to biochemical reactions. Through quantitative imaging analyses such as single …
Galectin-9 binds IgM-BCR to regulate B cell signaling
The galectin family of secreted lectins have emerged as important regulators of immune cell
function; however, their role in B-cell responses is poorly understood. Here we identify IgM …
function; however, their role in B-cell responses is poorly understood. Here we identify IgM …