A literature review of the patent publications on venetoclax–a selective Bcl-2 inhibitor: discovering the therapeutic potential of a novel chemotherapeutic agent

N Žigart, Z Časar - Expert Opinion on Therapeutic Patents, 2019 - Taylor & Francis
Introduction: Studies presented in patents show that a novel chemotherapeutic agent,
venetoclax, might be useful in additional therapeutic indications. Venetoclax is approved in …

Combination therapy for MDS

D Starczynowski, GW Rhyasen - US Patent 9,855,273, 2018 - Google Patents
Disclosed are compositions and methods for the treatment of disorders such as
myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). The disclosed …

Combination therapy for MDS

D Starczynowski, GW Rhyasen - US Patent 9,504,706, 2016 - Google Patents
Disclosed are compositions and methods for the treatment of disorders such as
myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). The disclosed …

Substituted Imidazo [1, 2-a]-pyridines as IRAK 1/4 and FLT3 inhibitors

DT Starczynowski, CJ Thomas, G Rhyasen… - US Patent …, 2023 - Google Patents
2021-04-27 Assigned to THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE
SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES reassignment THE …

Methods and compositions for treating mesothelioma and small lung cancer that express midkine

JA Whitsett, Y Maeda, T Fukazawa - US Patent 10,668,078, 2020 - Google Patents
US10668078B2 - Methods and compositions for treating mesothelioma and small lung cancer
that express midkine - Google Patents US10668078B2 - Methods and compositions for treating …

Methods and compositions to treat cancer

J Whitsett, Y Maeda - US Patent 10,391,084, 2019 - Google Patents
US10391084B2 - Methods and compositions to treat cancer - Google Patents
US10391084B2 - Methods and compositions to treat cancer - Google Patents Methods and …

Methods and compositions for treatment of myelodysplastic syndromes and/or acute myeloid leukemias

D Starczynowski, W Seibel, L Barreyro - US Patent 11,547,696, 2023 - Google Patents
Adams, AK, et al.,“DEK promotes HPV-positive and-negative head and neck cancer cell
proliferation,” Oncogene, 2015, 34: 868 877, 10 pgs. Adams, AK, et al.," IRAK1 is a novel …

Methods and compositions for treating mesothelioma and small lung cancer that express midkine

JA Whitsett, Y Maeda, T Fukazawa - US Patent 11,026,950, 2021 - Google Patents
Oligodeoxynucleotide Targeting Midkine: Its Design and Applica tion for Cancer Therapy, J.
Biol. Chem. 2002; 277: 23800-6, 7 pgs. Takeuchi K, et al., REI, ROS1 and ALK fusions in …

Methods and compositions for the treatment of head and neck cancer

S Wells, AK Adams, D Starczynowski - US Patent 10,487,329, 2019 - Google Patents
Disclosed are methods of treating a head and/or neck squamous cell carcinoma in an
individual. The method may include the step of administering to an individual a composition …

Methods and compositions for treatment of myelodysplastic syndromes and/or acute myeloid leukemias

D Starczynowski, W Seibel, L Barreyro - US Patent 11,752,136, 2023 - Google Patents
US11752136B2 - Methods and compositions for treatment of myelodysplastic syndromes
and/or acute myeloid leukemias - Google Patents US11752136B2 - Methods and compositions …