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Amplification-free CRISPR/Cas detection technology: challenges, strategies, and perspectives
Rapid and accurate molecular diagnosis is a prerequisite for precision medicine, food
safety, and environmental monitoring. The clustered regularly interspaced short palindromic …
safety, and environmental monitoring. The clustered regularly interspaced short palindromic …
MBenes for energy conversion: Advances, bottlenecks, and prospects
The advent of two-dimensional layered materials has bolstered the development of catalytic
endeavors for energy conversion and storage. MXenes (transition metal carbides/nitrides) …
endeavors for energy conversion and storage. MXenes (transition metal carbides/nitrides) …
A one-pot isothermal Cas12-based assay for the sensitive detection of microRNAs
The use of microRNAs as clinical cancer biomarkers is hindered by the absence of accurate,
fast and inexpensive assays for their detection in biofluids. Here we report a one-step and …
fast and inexpensive assays for their detection in biofluids. Here we report a one-step and …
A CRISPR/Cas12a-empowered surface plasmon resonance platform for rapid and specific diagnosis of the Omicron variant of SARS-CoV-2
The outbreak of the COVID-19 pandemic was partially due to the challenge of identifying
asymptomatic and presymptomatic carriers of the virus, and thus highlights a strong …
asymptomatic and presymptomatic carriers of the virus, and thus highlights a strong …
Ultrasensitive DNA origami plasmon sensor for accurate detection in circulating tumor DNAs
Early lung cancer screening by computed tomography is hampered by pulmonary nodules
caused by massive COVID‐19 infections, necessitating an ultrasensitive approach for the …
caused by massive COVID‐19 infections, necessitating an ultrasensitive approach for the …
Ultrasensitive and specific clustered regularly interspaced short palindromic repeats empowered a plasmonic fiber tip system for amplification-free monkeypox virus …
The urgent necessity for highly sensitive diagnostic tools has been accentuated by the
ongoing mpox (monkeypox) virus pandemic due to the complexity in identifying …
ongoing mpox (monkeypox) virus pandemic due to the complexity in identifying …
CRISPR/Cas-powered amplification-free detection of nucleic acids: current state of the art, challenges, and futuristic perspectives
Y Li, Y Liu, X Tang, J Qiao, J Kou, S Man, L Zhu… - ACS …, 2023 - ACS Publications
CRISPR/Cas system is becoming an increasingly influential technology that has been
repositioned in nucleic acid detection. A preamplification step is usually required to improve …
repositioned in nucleic acid detection. A preamplification step is usually required to improve …
CRISPR-Cas12a-empowered electrochemical biosensor for rapid and ultrasensitive detection of SARS-CoV-2 delta variant
Abstract Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The gold standard method …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The gold standard method …
Advanced mass spectrometric and spectroscopic methods coupled with machine learning for in vitro diagnosis
In vitro diagnosis (IVD) is one vital component of medical tests that detects biological
samples of tissues or bio‐fluids. Recently, mass spectrometry and spectroscopy have been …
samples of tissues or bio‐fluids. Recently, mass spectrometry and spectroscopy have been …
[HTML][HTML] Emerging two-dimensional materials: Synthesis, physical properties, and application for catalysis in energy conversion and storage
Inorganic, organic, and hybrid two-dimensional (2D) materials are being developed for ever-
expanding numbers of applications, though energy and catalysis remain the main drivers of …
expanding numbers of applications, though energy and catalysis remain the main drivers of …