Rapid and accurate molecular diagnosis is a prerequisite for precision medicine, food
safety, and environmental monitoring. The clustered regularly interspaced short palindromic …

Nucleic acid molecules possess many superior properties, including high designability and
structural predictability, making them attractive biosensing and bioimaging tools. The …

The outbreak of the COVID-19 pandemic was partially due to the challenge of identifying
asymptomatic and presymptomatic carriers of the virus, and thus highlights a strong …

The use of microRNAs as clinical cancer biomarkers is hindered by the absence of accurate,
fast and inexpensive assays for their detection in biofluids. Here we report a one-step and …

The urgent necessity for highly sensitive diagnostic tools has been accentuated by the
ongoing mpox (monkeypox) virus pandemic due to the complexity in identifying …

Abstract Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The gold standard method …

Infectious pathogens cause severe human illnesses and great deaths per year worldwide.
Rapid, sensitive, and accurate detection of pathogens is of great importance for preventing …

Guided, programmable, and target-activated nucleases, exemplified by Cas in the clustered
regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas) …

The pursuit of more sensitive, selective, multifunctional, portable and cost-effective
diagnostic tools has propelled biosensing technology to the forefront of clinical research …

CRISPR/Cas system is becoming an increasingly influential technology that has been
repositioned in nucleic acid detection. A preamplification step is usually required to improve …